Search
Deferiprone
go.drugbank.com/drugs/DB08826ApprovedInvestigationalThalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired. … Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1,2-Dimethyl-3-hydroxypyrid-4-one, 3-Hydroxy-1,2-dimethyl-4(1H)-pyridoneDehydroascorbic acid
go.drugbank.com/drugs/DB08830ExperimentalDehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in humans.
Categories: Vitamin C and analoguesSynonyms: L-threo-2,3-hexodiulosonic acid, γ-lactone, L-dehydroascorbate2-deoxyglucose
go.drugbank.com/drugs/DB08831InvestigationalAlthough there are several possible therapeutic indications for 2-deoxyglucose, presently there is no approved indication for 2-deoxyglucose as a therapeutic agent. … 2-deoxyglucose is predominantly used as a diagnostic agent in its radiolabelled form (fluorine-18 is used as the radiolabel).
Synonyms: 2-deoxy-D-glucose, 2-Deoxy-D-arabino-hexoseTaurochenodeoxycholic acid
go.drugbank.com/drugs/DB08833ExperimentalAs a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawnTauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration. … [A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and safety,[A249070] but a much higher hydrophilicity.
Agmatine
go.drugbank.com/drugs/DB08838ExperimentalAgmantine is a natural metabolite of the amino acid arginine. … As an investigational drug, it is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy between the
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 1-amino-4-guanidobutane, N-(4-aminobutyl)guanidineTyramine
go.drugbank.com/drugs/DB08841InvestigationalNutraceuticalTyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine.
Acetylcarnitine
go.drugbank.com/drugs/DB08842ApprovedInvestigationalAcetylcarnitine is an investigational drug in the United states, Italy, United Kingdom, China, Israel, and Norway, and it is approved in Italy, Portugal, Argentina, Chile, Philippines, Australia, and India. Acetylcarnitine can be synthes...
Mixtures: Live-wellâ„¢ MITOcareâ„¢ Liqfilâ„¢ Vegetable Capsule, Live-wellâ„¢ MEMOSENTIALâ„¢ CapsuleSynonyms: O-acetyl-L-carnitine, acetyl-L-carnitineGS 0573
go.drugbank.com/drugs/DB08843ExperimentalSynonyms: 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurineCategories: Heterocyclic Compounds, 2-RingOxogluric acid
go.drugbank.com/drugs/DB08845InvestigationalNutraceuticalIn the United States a phase I clinical trial is investigating whether oxogluric acid precursors found in nutritional supplements can benefit patients with the metabolic disorder propionic acidemia. … studies have shown a reduction in ammonia by oxogluric acid in hemodialysis patients.
Synonyms: 2-Ketoglutaric acid, 2-oxoglutaric acid