Tyramine

DB08841InvestigationalNutraceuticalSmall molecule

Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An... An important characteristic of this product is its impediment to cross the blood-brain barrier which restrains its side effects to only nonpsychoactive peripheral sympathomimetic effects.

Chemical structure of Tyramine
Formula / weight
C8H11NO · 137.179 g/mol (avg)
Code names
FEMA NO. 4215 · NSC-249188

Resolves to

Compound
UNIIX8ZC7V0OX3CAS51-67-2ChEMBLCHEMBL11608ChEBI15760PubChem5610KEGGC00483
Clinical / RWD
RxNorm10958
Structure
InChIKeyDZGWFCGJZKJUFP-UHFFFAOYSA-NSMILESNCCC1=CC=C(O)C=C1
Targets
Q96RJ0TAAR1
Transporters
O75751SLC22A3

What you can answer from here — as of August 30, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1TransporterSubstrate / inhibitor direction, not just membership
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725Drug interactionsStructured to mechanism, not free text
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6Clinical trialsPhase, status and sponsor resolved per trial
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Tyramine, and which of those have an active Phase 3 trial?

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