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Levamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178117, A178123] Levamisole was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis. … [A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer.
Products: OBAT CACING NO.17 KAM CEK SAN, PARAKS 40 MG/5 ML ŞURUP, 30 MLIopamidol
go.drugbank.com/drugs/DB08947ApprovedInvestigationalIopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.
Categories: Compounds used in a research, industrial, or household settingProducts: ยาฉีดไอโอปามิดอล 150, OYPALOMIN 150 INJECTIONKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Mixtures: Ixoba M, ONEMER DTCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesCiclopirox
go.drugbank.com/drugs/DB01188ApprovedInvestigationalCiclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses.
Products: NIBULEN 10 MG/G VAJİNAL KREM, 30 G, NIBULEN 10 MG/ML DERMAL ÇÖZELTİ, 20 MLAlprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigational[A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects of the drug which may lead to coma and death. … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.
Mixtures: Sentrazolam AM, NEUPAX DUO-SCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCytarabine
go.drugbank.com/drugs/DB00987ApprovedInvestigationalA pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. … Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 1-beta-D-Arabinofuranosylcytosine, cytosine-β-D-arabinofuranosideErythromycin
go.drugbank.com/drugs/DB00199ApprovedInvestigationalVet approvedErythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists … [L5245] Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive and gram-negative bacteria.
Mixtures: Sans-acne Solution, ILOTICINA DUO SOLUCION TOPICACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsAmoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approvedAmoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.
Mixtures: KLAVUPEN 625 MG 15 TABLET, AMOXICILINA + CLAVULANATO DE POTASIO 400 + 57 MG / 5 ML POLVO PARA RECONSTIUTIR A SUSPENSIÓN ORALCategories: Penicillin G, Cytochrome P-450 CYP2C8 InhibitorsCenobamate
go.drugbank.com/drugs/DB06119ApprovedInvestigationalCenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures. … [A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABA<sub>A</sub> and inhibits voltage gated sodium channels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: XCOPRI MAINTENANCE PACK 100 mg, 150 mg, XCOPRI TITRATION PACK 150 mg, 200 mgDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedA specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Mixtures: LACOMBI 15/10 MG KAPSUL, 28 ADET, DUOLANS 15/30 MG SR KAPSUL, 28 ADETCategories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 Substrates