Search

Displaying results 221 - 230 of 10000 in total
  1. Drug

    Aminophylline

    go.drugbank.com/drugs/DB01223
    ApprovedInvestigational

    The majority of aminophylline medications are discontinued and the remaining medications on the market are in short supply. … Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD.

    Categories: Xanthines and Adrenergics, aminophylline and adrenergicsProducts: AMINOPHYLLINE/DEMO INJECTION 250MG/10ML, AMINOPHYLLIN IV-FRESENIUS 250MG/10ML, INJECTION
  2. Drug

    Omfiloctocog alfa

    go.drugbank.com/drugs/DB19229
    Investigational

    Omfiloctocog alfa is under investigation in clinical trial NCT03947567 (Safety and Efficacy of Long-term Treatment With SCT800 in Previously Treated Hemophilia a Patients.).

    Synonyms: FACTOR VIII (FVIII, ANTIHEMOPHILIC FACTOR, AHF, PROCOAGULANT COMPONENT) WITH DELETED B-DOMAIN (746-1639)-SEQUENCE: SINGLE-CHAIN RECOMBINANT FVIII COMPOSED OF DOMAINS A1-A1-A2-A2 (1-740), THE B-DOMAIN N-AND
  3. Drug

    Lamivudine

    go.drugbank.com/drugs/DB00709
    ApprovedInvestigational

    It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). … A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring.

    Mixtures: Zidovex L (Lamivudine 150mg and Zidovudine 300mg Tablets), ARROW LZ (Lamivudine 150mg and Zidovudine 300mg ) TabletsCategories: lamivudine and abacavir, stavudine and lamivudine
  4. Drug

    Buprenorphine

    go.drugbank.com/drugs/DB00921
    ApprovedIllicitInvestigationalVet approved

    Combination with naloxone is intended to reduce the abuse potential of Suboxone, as naloxone is poorly absorbed by the oral route (and has no effect when taken orally), but would reverse the opioid agonist … [A186263,A186266,A186269] Buprenorphine acts as a partial mu-opioid receptor agonist with a high affinity for the receptor, but lower intrinsic activity compared to other full mu-opioid agonists such

    Synonyms: 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2-butanolMixtures: BUPREN 8MG/2MG SUBLINGUAL TABLET, SUBOXONE 2MG SUBLINGUAL TABLETS
  5. Drug

    Fosinopril

    go.drugbank.com/drugs/DB00492
    ApprovedInvestigational

    Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals … with diabetes mellitus and microalbuminuria or overt nephropathy.

    Mixtures: Fosinopril Sodium and Hydrochlorothiazide, Fosinopril Sodium and HydrochlorothiazideCategories: ACE Inhibitors and Diuretics, fosinopril and diuretics
  6. Drug

    Chlorpromazine

    go.drugbank.com/drugs/DB00477
    ApprovedInvestigationalVet approved

    Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. … Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.

    Synonyms: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  7. Drug

    Citalopram

    go.drugbank.com/drugs/DB00215
    ApprovedInvestigational

    [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230]

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Ng Citalopram, Nu-citalopram
  8. Drug

    Aripiprazole

    go.drugbank.com/drugs/DB01238
    ApprovedInvestigational

    [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism of alpha-adrenergic and 5-HT2A receptors. … [L45859,A4393] Aripiprazole was given FDA approval on November 15, 2002.[L6136]

    Categories: Aripiprazole and prodrugs, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Nb-aripiprazole, Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection
  9. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing, and geophagia. It is identified by the symbol _Zn_ [L2098]. … Understanding the mechanisms that control brain zinc homeostasis is, therefore, imperative to the development of preventive and treatment regimens for these and other neurological disorders [A32465].

    Mixtures: Zinc Chelate 20mg With Copper Chelate, Formula O-care Vitamin and Mineral SupplementCategories: Diet, Food, and Nutrition, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  10. Drug

    Aluminum sesquichlorohydrate

    go.drugbank.com/drugs/DB11108
    Approved

    Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts [A31171].

    Mixtures: Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN, Lactovit DEODORANT ROLL-ON MEN INVISIBLEProducts: Unlimited by Degree, Fraicheur Verveine Antiperspirant and Deodorant Roll-ON