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Displaying results 221 - 230 of 10000 in total
  1. Drug

    Levothyroxine

    go.drugbank.com/drugs/DB00451
    ApprovedInvestigational

    deiodination (by type I or type II 5′-deiodinases)[A179941] into its active metabolite T<sub>3</sub>. … [F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system.

    Synonyms: 3,5,3',5'-Tetraiodo-L-thyronine, T4Mixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADET, SYNTHROID® 112 MCG TABLETAS
  2. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    antihistamines, such as [diphenhydramine], which readily bind to off-targets that contribute to side effects such as sedation. … [L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation

    Products: MAYFEX 120 MG FILM TABLET, 10 ADET, FEXOFEN 60 MG FİLM TABLET, 10 ADET
  3. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US. … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.

    Mixtures: Metoprolol Tartrate and Hydrochlorothiazide 100 mg-50 mg, Metoprolol Tartrate and Hydrochlorothiazide 100 mg-25 mgCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Iomeprol

    go.drugbank.com/drugs/DB11705
    ApprovedInvestigational

    Iomeprol is a tri-iodinated, non-ionic radiographic contrast agent for intraarterial or intravenous use. Iomeprol demonstrates low chemotoxicity, osmolality and viscosity and high water solubility. Iomeprol first appeared in the market i...

    Synonyms: N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-5-(N-METHYLGLYCOLAMIDO)ISOPHTHALAMIDE, 1,3-BENZENEDICARBOXAMIDE, N,N'-BIS(2,3-DIHYDROXYPROPYL)-5-((HYDROXYACETYL)METHYLAMINO)-2,4,6-TRIIODO-Products: IOMERON 150 100 ML FLAKON, IOMERON 250 100 ML FLAKON
  5. Drug

    Coagulation Factor IX Human

    go.drugbank.com/drugs/DB13152
    ApprovedInvestigational

    Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.

    Mixtures: COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET, COFACT 500 IU/20 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADETProducts: Aımafıx 500 IU/10 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Toz ve Çözücü, Aımafıx 1000 IU/10 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Toz ve Çözücü, 1 ADET
  6. Drug

    Casdozokitug

    go.drugbank.com/drugs/DB17513
    Investigational

    Synonyms: immunoglobulin G1-kappa, anti-[IL27 (interleukin 27,IL27p28, IL27A)], Homo sapiens monoclonal antibody,gamma1 heavy chain Homo sapiens (1-456) [VH (Homo sapiens IGHV3-21*01 (95.9%) -(IGHD) -IGHJ5*02 (100%
  7. Drug

    Ciclesonide

    go.drugbank.com/drugs/DB01410
    ApprovedInvestigational

    Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.

    Mixtures: LUXNID 2/200 MCG INHALASYON IÇIN TOZ IÇIEREN KAPSÜL,60 KAPSÜL, LUXNID 2/400 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER ,60 DOZCategories: Agents to Treat Airway Disease, Cytochrome P-450 Substrates
  8. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    Later they continued to be investigated for use in heart failure throughout the 1970-1980s. … [A235865] The use of atenolol may need to be based on more patient factors than hypertension alone.[A235850,A235855,A235860,A235865]

    Mixtures: Apo-Atenidone Tablets 100/25 mg, TENORETIC 100 MG/25 MG FILM TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  9. Drug

    Ephedrine

    go.drugbank.com/drugs/DB01364
    ApprovedInvestigational

    [L12972] Ephedrine and [phenylephrine] are still used to treat hypotension, but their use in other indications has decreased due to the development of more selective adrenergic agonists.

    Mixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, ARTU 100 ML SURUPProducts: Ephedrin Meduna 10 mg/ml Injektionslösung, Ephedrin Kabi 10 mg/ml Injektionslösung
  10. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … [L7423] When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo or [hydrochlorothiazide].

    Mixtures: CO-HILOS FORT 100 MG/25 MG FILM TABLET, 28 ADET, CO-HILOS 50 MG/12.5 MG FILM TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors