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Nadroparin
go.drugbank.com/drugs/DB08813ApprovedInvestigationalWithdrawnThe amplification of the fibrin clotting cascade is stopped once factors Xa and IIa are inactivated. It is derived from porcine sources and has a mean molecular size of 5000 daltons. … Nadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa.
Products: FRAXIPARINE 0.3ML INJ 7,500 IC U AXA, FRAXIPARINE INJECTION 1900 IU AXA/0.2 mLMagaldrate
go.drugbank.com/drugs/DB08938ApprovedInvestigationalWithdrawnMagaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Mixtures: M A L D I MProducts: MAGALDRATO SPECIAL PRODUCT'S LINEFluorouracil
go.drugbank.com/drugs/DB00544ApprovedInvestigationalA pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Products: Adrucil Inj 50mg/ml, FLURO-5 DEVA 5000 MG/100 ML IV/IA ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 1 ADETEtoposide
go.drugbank.com/drugs/DB00773ApprovedInvestigationalAccumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding.
Categories: Topoisomerase II InhibitorsProducts: INJECTION ETOPOSIDE CS 100MG IN 5ML, Vepesid Inj 20mg/mlEsketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigationalThe FDA approved ketamine (Ketalar) in 1970. … [L5593] Esketamine may prove to be a promising treatment for patients diagnosed with major depressive disorder who have not experienced an improvement in symptoms despite treatment with various medications
Categories: Non-Competitive N-Methyl D-Aspartate (NMDA) Receptor AntagonistsProducts: Eskelan 25 mg/ml-Injektions-/Infusionslösung in Ampullen, Eskelan 25 mg/ml-Injektionslösung in DurchstechflaschenAmikacin
go.drugbank.com/drugs/DB00479ApprovedInvestigationalVet approvedM. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. … [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for the treatment of lung disease caused by Mycobacterium avium complex (MAC) bacteria in a small population
Synonyms: 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A, -D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)-Products: MIKASIN 100 MG/2 ML IM/IV 1 AMPUL, MIKASIN 100 MG/2 ML IM/IV AMPUL, 5 ADETGalcanezumab
go.drugbank.com/drugs/DB14042ApprovedInvestigational[L42060] It is unknown if galcanezumab has an effect on pregnancy outcomes. A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women.[L42060] … [A33112] Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive treatment of migraine and the treatment of episodic cluster headache.
Products: EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML, Pontevia 120 mg solution for injection in pre-filled penSodium bicarbonate
go.drugbank.com/drugs/DB01390ApprovedInvestigationalSodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Mixtures: E-Z-gas II, Iris Ink Eye DropsProducts: SAL DE FRUTAS LUA II, Sodium Bicarbonate Inj 4.2%Icatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigationalswelling, thus demonstrating bradykinin involvement in the disease pathophysiology. … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema.
Categories: Drugs Used in Hereditary AngioedemaProducts: Icatibant STADA 30 mg Injektionslösung in einer Fertigspritze, Icatibant Hikma 30 mg Injektionslösung in einer FertigspritzeKetamine
go.drugbank.com/drugs/DB01221ApprovedInvestigationalVet approvedIt started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic effects. … Ketamine is an NMDA receptor antagonist with a potent anesthetic effect.[A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories.
Categories: N-Methylaspartate, agonists, N-Methylaspartate, antagonists & inhibitorsProducts: Ketamin G.L. 10 mg/ml - Injektions-/Infusionslösung in Ampullen, Ketamin G.L. 50 mg/ml - Injektions-/Infusionslösung in Ampullen