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Depemokimab
go.drugbank.com/drugs/DB18846ApprovedInvestigational[A275338] Depemokimab blocks interleukin-5 (IL-5), a key cytokine that regulates eosinophil maturation, survival, and recruitment.
Octocrylene
go.drugbank.com/drugs/DB09535ApprovedHowever, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a variety of other products, like hair spray, tannin oil, BB cream, conditioner, and CC cream, among
Mixtures: Olay Luminous Whip Active Moisturizer Broad Spectrum SPF 30 Sales Samples, Olay Total Effects Whip Active Moisturizer Broad Spectrum SPF 30 Sunscreen Sales SamplesProducts: Panama Jack SPF 4 Dark Tanning OilDasatinib
go.drugbank.com/drugs/DB01254ApprovedInvestigationalDasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias. … [A11377] Unlike [imatinib], another tyrosine kinase used for the treatment of CML and Ph-positive ALL, dasatinib inhibits the active and inactive conformations of the ABL kinase domain.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesNemolizumab
go.drugbank.com/drugs/DB15252ApprovedInvestigational[A264254] By binding to IL-31RA, nemolizumab blocks the IL-31 signalling cascades that lead to inflammation. … Nemolizumab is a humanized monoclonal modified immunoglobulin 2 (IgG2) antibody directed against interleukin-31 receptor alpha (IL-31RA),[L51159] which is an endogenous cytokine implicated in the pathophysiology
Human immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIntravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and io...
Products: INTRAGAM P, BERIGLOBINA - PShark liver oil
go.drugbank.com/drugs/DB11088ApprovedShark oil is extracted from the livers of sharks, which can account for up to 25% of their total body weight. … Shark oil is a rich source of alkylglycerols and squalene, with relatively low amounts of n-3 polyunsaturated fatty acids.
Synonyms: Shark liver oilMixtures: Mineral Oil, Petrolatum, Phenylephrine Hydrochloride, Shark Liver Oil, Cocoa Butter, Phenylephrine Hydrochloride, Shark Liver OilBenralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigational[A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction. … Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils
Ustekinumab
go.drugbank.com/drugs/DB05679ApprovedInvestigationalUstekinumab is currently the first and only approved biologic therapy for ulcerative colitis that targets the interleukin (IL)-12 and IL-23 cytokines. … Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses.
Dupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigationalIt is also being studied in combination with another antibody that which targets IL-33.[L7225] … Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways.
Tezepelumab
go.drugbank.com/drugs/DB15090ApprovedInvestigationalBlocking the interaction of TSLP with the receptors TSLPR and IL-7Rα improves asthma-associated biomarkers including eosinophil counts and IgE, FeNO, IL-5, and IL-13 levels. … [A243764, A243769] Thymic stromal lymphopoietin (TSLP), an innate pleiotropic IL-2-family cytokine, has emerged as a key upstream regulator of chronic inflammation across asthma endotypes.