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Tenamfetamine
go.drugbank.com/drugs/DB01509IllicitInvestigationalIt is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally. [PubChem]
Hydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[A189753] Hydroxyzine is also used for generalized anxiety disorder, tension caused by psychoneurosis, and other conditions with manifestations of anxiety.[L9677]
Entrectinib
go.drugbank.com/drugs/DB11986ApprovedInvestigational[L8081] It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors.
Lotilaner
go.drugbank.com/drugs/DB17992ApprovedInvestigationalVet approved[A260741] On July 25, 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and only approved therapeutic for this condition.[L47551]
Ribavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalRibavirin is added to decrease relapse rates by accelerating viral clearance early in the treatment course [A19645].
Bendazac
go.drugbank.com/drugs/DB13501ApprovedWithdrawnBendazac is an oxyacetic acid . Despite possessing anti-inflammatory, anti-necrotic, choleretic, and anti-lipidemic characteristics, most research has revolved around studying and demonstrating the agent's principal action in inhibiting ...
AGRO100
go.drugbank.com/drugs/DB04998InvestigationalAGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells.
Cadaverine
go.drugbank.com/drugs/DB03854ExperimentalCadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine.
Lortalamine
go.drugbank.com/drugs/DB09187ExperimentalThis drug never made it past clinical trials, likely due to ocular toxicity in animals, but has been used in positron emission tomography studies to label norepinephrine transporters.
Temocapril
go.drugbank.com/drugs/DB08836InvestigationalTemocapril is a prodrug-type angiotensin-I converting enzyme (ACE) inhibitor not approved for use in the United States, but is approved in Japan and South Korea.