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Brensocatib
go.drugbank.com/drugs/DB15638Approved[A274348] Brensocatib was approved by the US FDA on August 12, 2025, for use in adults and pediatric patients with NCFB.[L53808,L53813] … [A274348] Brensocatib is a first-in-class dipeptidyl peptidase 1 (DPP1) inhibitor that inhibits neutrophil serine proteases, addressing a key driver of this inflammation.
CYT007-TNFQb
go.drugbank.com/drugs/DB05758ExperimentalCYT007-TNFQb is an active immunization therapy that aims at providing a novel treatment to people suffering from RA or psoriasis. … The vaccine should allow for administration of low amounts of drug to individual patients (in the microgram range) and for convenient dosing schedules.
Apadenoson
go.drugbank.com/drugs/DB05009InvestigationalApadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies.
Categories: Adenosine A receptor agonistsKAND567
go.drugbank.com/drugs/DB16511InvestigationalBecause COVID-19 involves cytotoxic cells associated with this pathway, KAND567 is currently being tested as a treatment for those with the illness[L32908]. … KAND567, a small molecule, blocks the fractaline (CX3CL1) receptor, which mediates the immune system response to inflammation[L32908].
Categories: Experimental Unapproved Treatments for COVID-19Sodium stibogluconate
go.drugbank.com/drugs/DB05630ApprovedInvestigationalSodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. … Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world, amphotericin or miltefosine are used instead.
Bromfenac
go.drugbank.com/drugs/DB00963ApprovedWithdrawnBromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. … Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes.
Gadofosveset trisodium
go.drugbank.com/drugs/DB06705ApprovedGadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. … The agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood vessels.
Categories: Compounds used in a research, industrial, or household settingCapsicum
go.drugbank.com/drugs/DB10897ApprovedCapsicum (Chili pepper) allergenic extract is used in allergenic testing.
Mixtures: C Ottways Lax Tab, Salonpas pain relieving HOT-LmRNA-1283
go.drugbank.com/drugs/DB22668ApprovedInvestigationala more targeted immune response and the use of a significantly smaller amount of mRNA per dose. … [L53413,A274083] mNEXSPIKE was approved by the US FDA in June 2025 for use in patients who have been previously vaccinated with any COVID-19 vaccine and who are at a higher risk of severe outcomes from
Treprostinil
go.drugbank.com/drugs/DB00374ApprovedInvestigational[L41855,L41860] The first agent approved for the treatment of PAH was [epoprostenol], a synthetic prostacyclin that significantly increases patients' quality of life. … Treprostinil was approved by the FDA in 2002 for the treatment of pulmonary arterial hypertension.