Bromfenac is an NSAID used to treat postoperative pain and inflammation of the eye. Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use.
- Mechanism
- Curator reviewed
The mechanism of its action is thought to be due to its ability to block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. Prostaglandins have been shown in many animal models to be mediators of certain kinds of intraocular inflammation. In studies performed in animal eyes, prostaglandins have been shown to produce disruption of the blood-aqueous humor barrier, vasodilation, increased vascular permeability, leukocytosis, and increased intraocular pressure.
- Primary indication
- For the treatment of postoperative inflammation in patients who have undergone cataract extraction.Curator reviewed · 2 structured indications
- Formula / weight
- C15H12BrNO3 · 334.165 g/mol (avg)
- First approval
- Canada, 2015 · United States, 2005 · European Union, 2016
- Code names
- ISV-303
- Brand names
Resolves to
ZBPLOVFIXSTCRZ-UHFFFAOYSA-NSMILESNC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1What you can answer from here — as of September 23, 2026
Which drugs share a target with Bromfenac, and which of those have an active Phase 3 trial?
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