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Displaying results 2301 - 2310 of 8974 in total
  1. Drug

    Raloxifene

    go.drugbank.com/drugs/DB00481
    ApprovedInvestigational

    However, due to the off-target actions by HRT, newer non-hormonal agents such as raloxifene and [tamoxifen] have been developed to reduce adverse events through selective pharmacological actions on tissue-specific … [A4977] Available in many countries worldwide, raloxifene was initially approved by the FDA in December, 1997 under the market name Evista® for the management and prevention of osteoporosis in postmenopausal

  2. Drug

    Retapamulin

    go.drugbank.com/drugs/DB01256
    Approved

    Retapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.

    Categories: Antibiotics for Topical Use
  3. Drug

    Urea C-14

    go.drugbank.com/drugs/DB09513
    ApprovedInvestigational

    To detect H. pylori, urea labeled with 14C is swallowed by the patient. … The UBT is indicated to confirm H. pylori infection and to monitor post-treatment for its eradication. Radiolabelled urea is available in two forms as 13C and 14C.

  4. Drug

    Daprodustat

    go.drugbank.com/drugs/DB11682
    ApprovedInvestigational

    anemia of CKD but not for non-dialysis patients with anemia of CKD. … [A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia.

  5. Drug

    Isosorbide dinitrate

    go.drugbank.com/drugs/DB00883
    ApprovedInvestigational

    Its actions are similar to nitroglycerin but with a slower onset of action.

    Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  6. Drug

    Betula pendula tar oil

    go.drugbank.com/drugs/DB11361
    ApprovedNutraceutical

    [L1113] By the FDA, it is considered under the substances approved to be added to the food. … Betula pendula tar oil is an essential oil found in the buds of the plant with the same name.

  7. Drug

    Trioxsalen

    go.drugbank.com/drugs/DB04571
    ApprovedWithdrawn

    In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage.[3] The compound is has been explored for development of antisense oligonucleotides that can be … cross-linked specifically to a mutant mRNA sequence without affecting normal transcripts differing at even a single base pair.

    Categories: Antipsoriatics for Systemic Use, Antipsoriatics for Topical Use
  8. Drug

    Abaloparatide

    go.drugbank.com/drugs/DB05084
    ApprovedInvestigational

    [L740] It was first approved by the FDA on April 28, 2017,[A256748] for the treatment of osteoporosis in postmenopausal women and is also used to increase bone density in men with osteoporosis. … [L740] It is a synthetic 34 amino acid peptide with 41% homology to human parathyroid hormone 1-34 and human PTHrP 1-34.

  9. Drug

    Fomivirsen

    go.drugbank.com/drugs/DB06759
    ApprovedWithdrawn

    The drug was withdrawn by the FDA because while there was a high unmet need for drugs to treat CMV when the drug was initially discovered and developed due to the CMV arising in people with AIDS, the development … Fomivirsen is marketed under the trade name Vitravene for intravitreal injection and was the first antisense drug to be approved by the Food and Drug Administration (FDA).

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    Felodipine is used to treat mild to moderate essential hypertension. … In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent

    Categories: Antihypertensive Agents Indicated for Hypertension