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15-hydroxyprostaglandin dehydrogenase [NAD(+)]
go.drugbank.com/bio_entities/BE0000552TargetEnzymeHumansCatalyzes the NAD-dependent dehydrogenation (oxidation) of a broad array of hydroxylated polyunsaturated fatty acids (mainly eicosanoids and docosanoids, including prostaglandins, lipoxins and resolvins), yielding their corresponding ket...
Polypeptides: 15-hydroxyprostaglandin dehydrogenase [NAD(+)]Synonyms: 15-PGDHPolyethylene glycol 400
go.drugbank.com/drugs/DB11077ApprovedInvestigationalIn addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788]. … [L1787] Polyethylene glycol 400 (PEG 400) is a low-molecular-weight grade of polyethylene glycol with a low-level toxicity.
Mixtures: Dg Lubricant Eye Drops, DG Lubricant Eye DropsCategories: Compounds used in a research, industrial, or household settingAnsuvimab
go.drugbank.com/drugs/DB16385ApprovedInfection with pathogenic filoviruses, such as _Zaire ebolavirus_ (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as … [A225933] Ansuvimab, formerly mAb114, is a fully human IgG1 mAb derived from a survivor of the 1995 Kikwit EBOV outbreak 11 years after infection, which displays strong glycan-independent binding to a
Resorcinol
go.drugbank.com/drugs/DB11085ApprovedInvestigationalIt is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses … Although it is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of formal therapeutic
Mixtures: BUCO-BLEU KOLLUTUVAR, 15 ML, DG Health Feminine Anti-itchSynonyms: m-Hydroquinone, m-hydroxyphenolCalaspargase pegol
go.drugbank.com/drugs/DB14730ApprovedInvestigationalCalaspargase pegol, also known as _asparlas_, is an asparagine specific enzyme which is indicated as a part of a multi-agent chemotherapy regimen for the treatment of ALL [L4890]. … The asparagine specific enzyme is derived from Escherichia coli, as a conjugate of L-asparaginase (L-asparagine amidohydrolase) and monomethoxypolyethylene glycol (mPEG) with a succinimidyl carbonate (
Categories: Compounds used in a research, industrial, or household settingElacestrant
go.drugbank.com/drugs/DB06374ApprovedInvestigational[L44918,L44948] It received a similar approval in the EU in September 2023. … Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesPegloticase
go.drugbank.com/drugs/DB09208ApprovedInvestigationalPegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. … [A249980] The PEG group also gives pegloticase a lower potential to induce an immune response.
Categories: Compounds used in a research, industrial, or household settingEtesevimab
go.drugbank.com/drugs/DB15897InvestigationalEtesevimab (LY-CoV016, also known as JS016) is a fully human and recombinant monoclonal antibody that targets the SARS-CoV-2 surface spike protein receptor binding domain. … progressing to severe COVID-19:[L40179] this EUA later expanded in December 2021 to include all younger children at high risk, including newborns.
Lusutrombopag
go.drugbank.com/drugs/DB13125ApprovedInvestigationalx 10^9/L were administered lusutrombopag orally [L4166]. … In two randomized, double-blind, placebo-controlled trials, patients with chronic liver disease and severe thrombocytopenia who were undergoing an invasive procedure with a platelet count less than 50
Citrus bioflavonoids
go.drugbank.com/drugs/DB14586ApprovedMixtures: VITAMIN C 1000 MG WITH BIOFLAVONOIDS 100 MG, Rose Hips 500plus Nu Life