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Atoltivimab
go.drugbank.com/drugs/DB15898ApprovedInvestigationalEbola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. … INMAZEB™ is produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020.[L17320]
mRNA-1010
go.drugbank.com/drugs/DB22484Approved[L64058] The FDA approved mFLUSIVA on August 5, 2026 for active immunization against influenza in adults 50 years of age and older, making it the first mRNA-based influenza vaccine approved in the United … [L64058,L64059,L64060] Full approval applies to adults 50 through 64 years, while the indication for adults 65 years and older was granted accelerated approval based on immune responses, with clinical
Categories: Complex MixturesIbalizumab
go.drugbank.com/drugs/DB12698ApprovedInvestigationalIt is an advanced and current antibody in development for the treatment of HIV/AIDS. It has been developed by Taimed biologics and Theratechnologies [L1558, L1554]. … This drug was approved in March 2018 for the management of treatment-resistant HIV [L1554].
Padimate A
go.drugbank.com/drugs/DB11229ApprovedWithdrawnIn Europe this chemical was withdrawn in 1989 for unstated reasons and in the US it was never approved for use in sunscreens. … Padimate A is an ester derivative of PABA and an ingredient in some sunscreens.
Cytochrome b-c1 complex subunit 8
go.drugbank.com/bio_entities/BE0003857TargetHumansThe respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
Polypeptides: Cytochrome b-c1 complex subunit 8Synonyms: Complex III subunit 8, Complex III subunit VIIICytochrome b-c1 complex subunit 9
go.drugbank.com/bio_entities/BE0003861TargetHumansThe respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
Polypeptides: Cytochrome b-c1 complex subunit 9Synonyms: Complex III subunit 9, Complex III subunit XCytochrome b6-f complex subunit 5
go.drugbank.com/bio_entities/BE0003906TargetMastigocladus laminosusPetG is required for either the stability or assembly of the cytochrome b6-f complex. … Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
Polypeptides: Cytochrome b6-f complex subunit 5Synonyms: Cytochrome b6-f complex subunit V, Cytochrome b6-f complex subunit PetGFatty acid oxidation complex subunit alpha
go.drugbank.com/bio_entities/BE0004256TargetPseudomonas fragiInvolved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-Co...
Polypeptides: Fatty acid oxidation complex subunit alphaTrafficking protein particle complex subunit 4
go.drugbank.com/bio_entities/BE0004278TargetHumansCore component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase (Probable).
Polypeptides: Trafficking protein particle complex subunit 4Trafficking protein particle complex subunit 1
go.drugbank.com/bio_entities/BE0004279TargetHumansMay play a role in vesicular transport from endoplasmic reticulum to Golgi
Polypeptides: Trafficking protein particle complex subunit 1