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Nepidermin
go.drugbank.com/drugs/DB14145InvestigationalSynonyms: H-EGFInternational brands: Kang He Su, Regen-DL-Acetylleucine
go.drugbank.com/drugs/DB16956ApprovedInvestigationalLevacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo. … [A264439] Observational studies in patients with Niemann-Pick disease type C (NPC) suggested a beneficial symptomatic as well as neuroprotective disease-modifying effect of the DL-form of N-acetylleucine
Synonyms: Acetylleucine, (s)-, (s)-2-acetamido-4-methylpentanoic acidCategories: P-glycoprotein inhibitorsVanzacaftor
go.drugbank.com/drugs/DB18373ApprovedInvestigationalVanzacaftor is a small molecule cystic fibrosis transmembrane conductance regulator (CFTR) corrector. … ], a CFTR potentiator, for the treatment of patients with responsive CFTR mutations.
Synonyms: VX-121Oxcarbazepine
go.drugbank.com/drugs/DB00776ApprovedInvestigational- a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the name [eslicarbazepine]. … [L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood
Synonyms: 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamideCategories: P-glycoprotein inducers, P-glycoprotein substratesTestosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationals Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector [L4659]. … Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate.
Mixtures: NOFERTYL® INYECTABLECategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesDatopotamab deruxtecan
go.drugbank.com/drugs/DB16410ApprovedInvestigationalDatopotamab deruxtecan is an antibody-drug conjugate comprising a Trop-2-directed monoclonal antibody (datopotamab) and a DNA topoisomerase-I inhibitor, DDx.
Categories: Topoisomerase I Inhibitors, MATE 2 SubstratesTaurolidine
go.drugbank.com/drugs/DB12473ApprovedInvestigationalTaurolidine is an antimicrobial used for the prevention of catheter-related infections. It is a derivative of the amino acid [taurine]. … and Antifungal Drugs (LPAD pathway) for the prevention of catheter-related bloodstream infections in a limited and specific patient population.
Categories: Heterocyclic Compounds, 1-RingProducts: Taurolin (Taurolidin "Geistlich") 2% - InstillationslösungGold
go.drugbank.com/drugs/DB14154InvestigationalA yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration.
Mixtures: HydroGold 9, Medi SM 24K Gold Hydrogel Peptide Mask PackDeutivacaftor
go.drugbank.com/drugs/DB15141ApprovedInvestigationalDeutivacaftor is a small molecule cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. … It is used alongside CFTR correctors to increase the quantity and function of CFTR at the cell surface in patients with cystic fibrosis.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsThiosulfuric acid
go.drugbank.com/drugs/DB09499ApprovedInvestigational[A252827] Sodium thiosulfate is approved for the treatment of acute cyanide poisoning[L310,L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). … Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching
Synonyms: Sulfurothioic S-acidMixtures: Sodium Polysulthionate, 5-mthf, Sodium polysulthionate, 5-methyltetrahydrofolate