Nepidermin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Nepidermin
DrugBank Accession Number
DB14145
Background

Not Available

Type
Biotech
Groups
Experimental
Synonyms
  • Beta-urogastrone
  • Epidermal growth factor (human)
  • Epidermal growth factor biosynthetic human
  • Epidermal growth factor human
  • H-EGF
  • Human EGF
  • Human epidermal growth factor
  • Human urogastrone
  • Nepidermin
  • Nepidermina
  • N├ępidermine
  • Nepiderminum
  • Recombinant human epidermal growth factor
  • rhEGF
  • Urogastrone

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
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Associated Conditions
Associated Therapies
Contraindications & Blackbox Warnings
Contraindications
Avoid life-threatening adverse drug events
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Avoid life-threatening adverse drug events & improve clinical decision support.
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products2
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International/Other Brands
Easyef / Genesoft / Kang He Su / Regen-D
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
EASYDEW DW EGF Derma Needle 3000 ShotSolution0.000045 mg/45mgTopicalDn Company Co.,Ltd.2018-03-01Not applicableUS flag
Easydew EX Repair Control Repair Control EgfLiquid0.0002 g/20mLTopicalDn Company Co.,Ltd.2018-02-01Not applicableUS flag
EASYDEW EX REPAIR CONTROL REPAIR CONTROL EGF 3mLLiquid0.03 mg/3mLTopicalDn Company Co.,Ltd.2018-07-01Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ARTEMES 3R Effect Hyaluronic AmpouleNepidermin (0.05 mg/5mL) + Adenosine (0.002 g/5mL) + Nicotinamide (0.10 g/5mL)LiquidTopicalDn Company Co.,Ltd.2019-03-01Not applicableUS flag
Artemes 3R effect hyaluronic maskNepidermin (0.33 mg/33g) + Adenosine (0.01 g/33g) + Nicotinamide (0.66 g/33g)PatchTopicalDn Company Co.,Ltd.2019-03-01Not applicableUS flag
Cosmeceutical Mask PackNepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)PatchTopicalYBK Investment, INC2013-10-21Not applicableUS flag
Cosmeceutical Mask PackNepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)PatchTopicalYBK Investment, INC2013-10-212013-10-29US flag
Dermaheal Cosmeceutical Mask Pack PlusNepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)PatchTopicalYBK Investment, INC2013-10-21Not applicableUS flag
EASYDEW DW EGF Derma Oneshot AmpouleNepidermin (0.000001 mg/1.2mL) + Adenosine (0.00048 mg/1.2mL) + Nicotinamide (0.024 mg/1.2mL)LiquidTopicalDn Company Co.,Ltd.2018-03-01Not applicableUS flag
Easydew EX Repair Control Active Soothing SerumNepidermin (0.00012 g/40mL) + Adenosine (0.016 g/40mL) + Nicotinamide (0.8 g/40mL)CreamTopicalDn Company Co.,Ltd.2018-02-01Not applicableUS flag
Easydew EX Repair Control Renewal MoistureNepidermin (0.0001 g/50mL) + Adenosine (0.02 g/50mL) + Nicotinamide (1.0 g/50mL)CreamTopicalDn Company Co.,Ltd.2018-02-01Not applicableUS flag
Le-Blen EGF SerumNepidermin (0.54 g/56.7g) + Sodium hyaluronate (0.4 g/56.7g)LotionTopicalLeBlen Beauty Inc2018-04-24Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ARTEMES 3R Effect Hyaluronic AmpouleNepidermin (0.05 mg/5mL) + Adenosine (0.002 g/5mL) + Nicotinamide (0.10 g/5mL)LiquidTopicalDn Company Co.,Ltd.2019-03-01Not applicableUS flag
Artemes 3R effect hyaluronic maskNepidermin (0.33 mg/33g) + Adenosine (0.01 g/33g) + Nicotinamide (0.66 g/33g)PatchTopicalDn Company Co.,Ltd.2019-03-01Not applicableUS flag
Cosmeceutical Mask PackNepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)PatchTopicalYBK Investment, INC2013-10-21Not applicableUS flag
Cosmeceutical Mask PackNepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)PatchTopicalYBK Investment, INC2013-10-212013-10-29US flag
Dermaheal Cosmeceutical Mask Pack PlusNepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)PatchTopicalYBK Investment, INC2013-10-21Not applicableUS flag
EASYDEW DW EGF Derma Needle 3000 ShotNepidermin (0.000045 mg/45mg)SolutionTopicalDn Company Co.,Ltd.2018-03-01Not applicableUS flag
EASYDEW DW EGF Derma Oneshot AmpouleNepidermin (0.000001 mg/1.2mL) + Adenosine (0.00048 mg/1.2mL) + Nicotinamide (0.024 mg/1.2mL)LiquidTopicalDn Company Co.,Ltd.2018-03-01Not applicableUS flag
Easydew EX Repair Control Active Soothing SerumNepidermin (0.00012 g/40mL) + Adenosine (0.016 g/40mL) + Nicotinamide (0.8 g/40mL)CreamTopicalDn Company Co.,Ltd.2018-02-01Not applicableUS flag
Easydew EX Repair Control Renewal MoistureNepidermin (0.0001 g/50mL) + Adenosine (0.02 g/50mL) + Nicotinamide (1.0 g/50mL)CreamTopicalDn Company Co.,Ltd.2018-02-01Not applicableUS flag
Easydew EX Repair Control Repair Control EgfNepidermin (0.0002 g/20mL)LiquidTopicalDn Company Co.,Ltd.2018-02-01Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
TZK30RF92W
CAS number
62253-63-8

References

General References
Not Available
RxNav
1427157
Wikipedia
Nepidermin

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3CompletedTreatmentDiabetic Foot Ulcer Patients With Uncontrolled Diabetes Mellitus1
3Unknown StatusTreatmentDiabetic Foot Ulcers (DFUs) / Epidermal Growth Factor1
3Unknown StatusTreatmentStomatitis1
2CompletedPreventionOral Mucositis1
2CompletedTreatmentColorectal Carcinoma (CRC)1
2Not Yet RecruitingTreatmentNeoplasms, Breast1
2RecruitingTreatmentHER2/Neu+ Uterine Serous Carcinoma1
1CompletedOtherHealthy Subjects (HS)1
1RecruitingTreatmentPeriodontitis1
1, 2RecruitingTreatmentAdvanced Head and Neck Squamous Cell Carcinoma / Metastatic Non-Small Cell Lung Cancer / Non-Small Cell Lung Carcinoma (NSCLC) / PD-L1 positive / Recurrent Head and Neck Squamous Cell Carcinoma / Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 / Stage III Lung Cancer AJCC v8 / Stage IIIA Lung Cancer AJCC v8 / Stage IIIB Lung Cancer AJCC v8 / Stage IIIC Lung Cancer AJCC v8 / Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 / Stage IV Lung Cancer AJCC v8 / Stage IVA Lung Cancer AJCC v8 / Stage IVB Lung Cancer AJCC v8 / Unresectable Non-Small Cell Lung Carcinoma1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
PatchTopical
SolutionTopical0.000045 mg/45mg
LiquidTopical
CreamTopical
LiquidTopical0.0002 g/20mL
LiquidTopical0.03 mg/3mL
SolutionTopical
SolutionTopical0.5 mg/ml
SprayTopical
Injection, powder, lyophilized, for solutionIntralesional
LotionTopical
GelTopical
Powder0.075 mg/1vial
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on June 27, 2018 20:17 / Updated on February 21, 2021 18:54