This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Nepidermin
- DrugBank Accession Number
- DB14145
- Background
Not Available
- Type
- Biotech
- Groups
- Experimental
- Synonyms
- Beta-urogastrone
- Epidermal growth factor (human)
- Epidermal growth factor biosynthetic human
- Epidermal growth factor human
- H-EGF
- Human EGF
- Human epidermal growth factor
- Human urogastrone
- Nepidermin
- Nepidermina
- Népidermine
- Nepiderminum
- Recombinant human epidermal growth factor
- rhEGF
- Urogastrone
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
- Associated Therapies
- Contraindications & Blackbox Warnings
- Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- International/Other Brands
- Easyef / Genesoft / Kang He Su / Regen-D
- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image EASYDEW DW EGF Derma Needle 3000 Shot Solution 0.000045 mg/45mg Topical Dn Company Co.,Ltd. 2018-03-01 Not applicable US Easydew EX Repair Control Repair Control Egf Liquid 0.0002 g/20mL Topical Dn Company Co.,Ltd. 2018-02-01 Not applicable US EASYDEW EX REPAIR CONTROL REPAIR CONTROL EGF 3mL Liquid 0.03 mg/3mL Topical Dn Company Co.,Ltd. 2018-07-01 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ARTEMES 3R Effect Hyaluronic Ampoule Nepidermin (0.05 mg/5mL) + Adenosine (0.002 g/5mL) + Nicotinamide (0.10 g/5mL) Liquid Topical Dn Company Co.,Ltd. 2019-03-01 Not applicable US Artemes 3R effect hyaluronic mask Nepidermin (0.33 mg/33g) + Adenosine (0.01 g/33g) + Nicotinamide (0.66 g/33g) Patch Topical Dn Company Co.,Ltd. 2019-03-01 Not applicable US Cosmeceutical Mask Pack Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g) Patch Topical YBK Investment, INC 2013-10-21 2013-10-29 US Cosmeceutical Mask Pack Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g) Patch Topical YBK Investment, INC 2013-10-21 Not applicable US Dermaheal Cosmeceutical Mask Pack Plus Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g) Patch Topical YBK Investment, INC 2013-10-21 Not applicable US EASYDEW DW EGF Derma Oneshot Ampoule Nepidermin (0.000001 mg/1.2mL) + Adenosine (0.00048 mg/1.2mL) + Nicotinamide (0.024 mg/1.2mL) Liquid Topical Dn Company Co.,Ltd. 2018-03-01 Not applicable US Easydew EX Repair Control Active Soothing Serum Nepidermin (0.00012 g/40mL) + Adenosine (0.016 g/40mL) + Nicotinamide (0.8 g/40mL) Cream Topical Dn Company Co.,Ltd. 2018-02-01 Not applicable US Easydew EX Repair Control Renewal Moisture Nepidermin (0.0001 g/50mL) + Adenosine (0.02 g/50mL) + Nicotinamide (1.0 g/50mL) Cream Topical Dn Company Co.,Ltd. 2018-02-01 Not applicable US Le-Blen EGF Serum Nepidermin (0.54 g/56.7g) + Sodium hyaluronate (0.4 g/56.7g) Lotion Topical LeBlen Beauty Inc 2018-04-24 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ARTEMES 3R Effect Hyaluronic Ampoule Nepidermin (0.05 mg/5mL) + Adenosine (0.002 g/5mL) + Nicotinamide (0.10 g/5mL) Liquid Topical Dn Company Co.,Ltd. 2019-03-01 Not applicable US Artemes 3R effect hyaluronic mask Nepidermin (0.33 mg/33g) + Adenosine (0.01 g/33g) + Nicotinamide (0.66 g/33g) Patch Topical Dn Company Co.,Ltd. 2019-03-01 Not applicable US Cosmeceutical Mask Pack Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g) Patch Topical YBK Investment, INC 2013-10-21 Not applicable US Cosmeceutical Mask Pack Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g) Patch Topical YBK Investment, INC 2013-10-21 2013-10-29 US Dermaheal Cosmeceutical Mask Pack Plus Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g) Patch Topical YBK Investment, INC 2013-10-21 Not applicable US EASYDEW DW EGF Derma Needle 3000 Shot Nepidermin (0.000045 mg/45mg) Solution Topical Dn Company Co.,Ltd. 2018-03-01 Not applicable US EASYDEW DW EGF Derma Oneshot Ampoule Nepidermin (0.000001 mg/1.2mL) + Adenosine (0.00048 mg/1.2mL) + Nicotinamide (0.024 mg/1.2mL) Liquid Topical Dn Company Co.,Ltd. 2018-03-01 Not applicable US Easydew EX Repair Control Active Soothing Serum Nepidermin (0.00012 g/40mL) + Adenosine (0.016 g/40mL) + Nicotinamide (0.8 g/40mL) Cream Topical Dn Company Co.,Ltd. 2018-02-01 Not applicable US Easydew EX Repair Control Renewal Moisture Nepidermin (0.0001 g/50mL) + Adenosine (0.02 g/50mL) + Nicotinamide (1.0 g/50mL) Cream Topical Dn Company Co.,Ltd. 2018-02-01 Not applicable US Easydew EX Repair Control Repair Control Egf Nepidermin (0.0002 g/20mL) Liquid Topical Dn Company Co.,Ltd. 2018-02-01 Not applicable US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- TZK30RF92W
- CAS number
- 62253-63-8
References
- General References
- Not Available
- External Links
- 1427157
- Wikipedia
- Nepidermin
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Completed Treatment Diabetic Foot Ulcer Patients With Uncontrolled Diabetes Mellitus 1 3 Unknown Status Treatment Diabetic Foot Ulcers (DFUs) / Epidermal Growth Factor 1 3 Unknown Status Treatment Stomatitis 1 2 Completed Prevention Oral Mucositis 1 2 Completed Treatment Colorectal Cancer 1 2 Recruiting Treatment Breast Neoplasms 1 2 Recruiting Treatment HER2/Neu+ Uterine Serous Carcinoma 1 1 Completed Other Healthy Subjects (HS) 1 1 Completed Screening Dry Eye Syndrome (DES) 1 1 Completed Treatment Adenocarcinomas / Breast Cancer / Breast Neoplasms / Metastatic Solid Tumors Characterized by HER2/Neu Expression 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Patch Topical Solution Topical 0.000045 mg/45mg Liquid Topical Cream Topical Liquid Topical 0.0002 g/20mL Liquid Topical 0.03 mg/3mL Solution Topical Solution Topical 0.5 mg/ml Spray Topical Injection, powder, lyophilized, for solution Intralesional 75 mcg Lotion Topical Gel Topical 150 mcg/g Gel Topical Powder 0.075 mg/1vial - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at June 27, 2018 20:17 / Updated at May 04, 2022 16:30