Search
Tegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawnNovartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C). … [L5918,F4229] Since then, closer evaluations of the original data suggesting such cardiovascular risk have resulted in the limited reintroduction or 're-approval' of tegaserod for treatment of IBS-C specifically
Categories: Drugs for Constipation, Serotonin-4 Receptor AgonistAcetyl sulfisoxazole
go.drugbank.com/drugs/DB14033ApprovedVet approvedSulfisoxazole acetyl competes with PABA for the bacterial enzyme, _dihydropteroate synthase_, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid.
Methadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalThese effects make methadone a good option for the treatment of severe pain and addiction as fewer doses are needed to maintain analgesia and prevent opioid withdrawal symptoms. … [F4685,F4688,F4691,A185885,A185900,A185903] Due to its unique mechanism of action, methadone is particularly useful for the management of hard to treat pain syndromes such as neuropathic pain and cancer
Categories: NMDA Receptor AntagonistsAficamten
go.drugbank.com/drugs/DB18490ApprovedInvestigational[L54788] Approved by the FDA on December 19, 2025, aficamten is indicated for the treatment of adults with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) to improve functional capacity and
Meningococcal polysaccharide vaccine group Y
go.drugbank.com/drugs/DB13888ApprovedInvestigationalMeningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup Y. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis a...
Mixtures: MENVEO POWDER & SOLUTION FOR SOLUTION FOR INJECTION, Menveo Powder and Solution for Solution for Injectionbeta-Hydroxybutyric acid
go.drugbank.com/drugs/DB16506Investigational(completed for type 1 diabetes), and NCT05581043 (completed for type 2 diabetes). … Beta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236
Categories: Experimental Unapproved Treatments for COVID-19Pinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalPinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable
Categories: Drugs for Functional Gastrointestinal DisordersUrea C-14
go.drugbank.com/drugs/DB09513ApprovedInvestigationalIt is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as PyTest) for the detection of Helicobacter pylori infections. … Exhaled breath samples can then be collected and measured for the presence of radioactivity.
Dermatophagoides farinae
go.drugbank.com/drugs/DB10400ApprovedInvestigationalThis combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies. … Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy.
Dermatophagoides pteronyssinus
go.drugbank.com/drugs/DB10401ApprovedInvestigationalThis combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies. … Dermatophagoides pteronyssinus extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy.