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Displaying results 2321 - 2330 of 10000 in total
  1. Drug

    Fluocortin

    go.drugbank.com/drugs/DB13223
    Experimental

    Fluocortin has been studied as a corticosteroid for treatment of dermatitis and eczema Spain [A174817].

    Categories: Corticosteroids, Moderately Potent (Group II)
  2. Drug

    Fluperolone

    go.drugbank.com/drugs/DB13491
    Experimental

    Categories: Corticosteroids, Moderately Potent (Group II)
  3. Drug

    Catumaxomab

    go.drugbank.com/drugs/DB06607
    ApprovedWithdrawn

    Catumaxumab is a trifunctional monoclonal antibody developed for use in cancer treatment. It has affinity for T-cells, accessory immune cells, and cancer cells. … It is currently available under the brand name Removab.

  4. Drug

    Quazepam

    go.drugbank.com/drugs/DB01589
    ApprovedIllicit

    Quazepam is a trifluoroethyl benzodiazepine derivative. It was first approved in the US in 1985 and is used as a hypnotic for the treatment of insomnia. … [L44913] It appears to be unique amongst other benzodiazepine derivatives in its relatively high affinity for sleep-promoting α1 subunit-containing GABA<sub>A</sub> receptors and low affinity for other

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  5. Drug

    Nepidermin

    go.drugbank.com/drugs/DB14145
    Investigational

    Synonyms: H-EGFInternational brands: Kang He Su, Regen-D
  6. Drug

    L-Acetylleucine

    go.drugbank.com/drugs/DB16956
    ApprovedInvestigational

    Levacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo. … [A264439] Observational studies in patients with Niemann-Pick disease type C (NPC) suggested a beneficial symptomatic as well as neuroprotective disease-modifying effect of the DL-form of N-acetylleucine

    Synonyms: Acetylleucine, (s)-, (s)-2-acetamido-4-methylpentanoic acidCategories: P-glycoprotein inhibitors
  7. Drug

    Gilteritinib

    go.drugbank.com/drugs/DB12141
    ApprovedInvestigational

    [A40036] It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other therapies. … Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group.

    Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesProducts: XOSPATA® FILM-COATED TABLETS 40MG
  8. Drug

    Vanzacaftor

    go.drugbank.com/drugs/DB18373
    ApprovedInvestigational

    Vanzacaftor is a small molecule cystic fibrosis transmembrane conductance regulator (CFTR) corrector. … ], a CFTR potentiator, for the treatment of patients with responsive CFTR mutations.

    Synonyms: VX-121
  9. Drug

    Oxcarbazepine

    go.drugbank.com/drugs/DB00776
    ApprovedInvestigational

    - a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the name [eslicarbazepine]. … [L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood

    Synonyms: 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamideCategories: P-glycoprotein inducers, P-glycoprotein substrates
  10. Drug

    Testosterone enanthate

    go.drugbank.com/drugs/DB13944
    ApprovedInvestigational

    s Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector [L4659]. … Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate.

    Mixtures: NOFERTYL® INYECTABLECategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates