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Remimazolam
go.drugbank.com/drugs/DB12404ApprovedInvestigational[L14647] Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as [remifentanil], are designed to be metabolically fragile and thus … [A214857] These "soft drugs" are useful in the context of surgical procedures, wherein a rapid onset/offset is desirable, enabling anesthesiologists to manipulate drug concentrations as needed.
Categories: Heterocyclic Compounds, 2-RingCholine
go.drugbank.com/drugs/DB00122ApprovedInvestigationalNutraceuticalIt is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. … A basic constituent of lecithin that is found in many plants and animal organs.
Mixtures: KORDEL`S EXECUTIVE B TABLET, KORDEL`S EXECUTIVE B + C TABLETCategories: Vitamin B ComplexItraconazole
go.drugbank.com/drugs/DB01167ApprovedInvestigationalFirst synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. … While the intravenous formulation of the drug was formerly available, it was discontinued in the US in 2007.[A263232]
Mixtures: Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4%, Ciclopirox 3% / Itraconazole 5% / Urea 20%Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesViomycin
go.drugbank.com/drugs/DB06827ApprovedViomycin is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it was replaced by the less toxic capreomycin. … Viomycin was derived from the actinomycete _Streptomyces puniceus_.
Synonyms: Vinacetin ACarisoprodol
go.drugbank.com/drugs/DB00395Approvedfor abuse in addition to a low risk of dependence [L5074]. … In January 2012, this drug was classified as a Schedule IV substance under the controlled substances act in several US states due to alarming rates of abuse [A176062, A176077] despite having a low potential
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesSynonyms: N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate, (RS)-2-{[(aminocarbonyl)oxy]methyl}-2-methylpentyl isopropylcarbamateCentanafadine
go.drugbank.com/drugs/DB14841ApprovedInvestigationalCentanafadine is a reuptake inhibitor at the norepinephrine, dopamine, and serotonin transporters and a central nervous system stimulant. … [L63934] The FDA approved centanafadine on July 24, 2026, for the treatment of ADHD in adults and pediatric patients 6 years of age and older weighing at least 20 kg; use is not recommended below that
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeVericiguat
go.drugbank.com/drugs/DB15456ApprovedInvestigational[A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis and thereby helps to prevent the myocardial and vascular dysfunction associated with decreased sGC … Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations.
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: VERQUVO® 5MG TABLETAS RECUBIERTAS, VERQUVO® 10MG TABLETAS RECUBIERTASCetrorelix
go.drugbank.com/drugs/DB00050ApprovedInvestigationalCetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). … GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle.
Products: CETROTIDE 250 MCG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET, CETROTIDE 250 MCG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 7 ADETBrincidofovir
go.drugbank.com/drugs/DB12151ApprovedInvestigationalIt is a lipid conjugate pro-drug of the acyclic nucleotide analogue [cidofovir][L34404,A235725] - this lipid conjugate improves drug delivery to the target cells and significantly reduces the nephrotoxicity … Brincidofovir is an oral antiviral drug used in the treatment of human smallpox infections.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Heterocyclic Compounds, 1-RingGolodirsen
go.drugbank.com/drugs/DB15593ApprovedInvestigationalGolodirsen is a morpholino antisense oligomer designed to treat about 8% of patients with Duchenne Muscular Dystrophy (DMD). … [A188580,T756] A similar drug used in the treatment of other types of DMD is [eteplirsen], which targets a different genetic mutation.
Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting