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Tamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigationalTamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations. … [A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799]
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine, (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamineGlutethimide
go.drugbank.com/drugs/DB01437ApprovedIllicitGlutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-Ethyl-2-phenylglutarimideAV-101
go.drugbank.com/drugs/DB12878InvestigationalAV-101 has been used in trials studying the treatment of Neuropathic Pain.
Synonyms: (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid, L-4-CL-KYNN-{2-[(4'-CYANO-1,1'-BIPHENYL-4-YL)OXY]ETHYL}-N'-HYDROXY-N-METHYLUREA
go.drugbank.com/drugs/DB06971ExperimentalSynonyms: N-{2-[(4'-CYANO-1,1'-BIPHENYL-4-YL)OXY]ETHYL}-N'-HYDROXY-N-METHYLUREA2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
go.drugbank.com/drugs/DB08360ExperimentalSynonyms: 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILEFluorescein
go.drugbank.com/drugs/DB00693ApprovedInvestigationalA phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal
Synonyms: 3',6'-dihydroxyfluoran, 9-(o-carboxyphenyl)-6-hydroxy-3H-xanthen-3-oneCategories: Heterocyclic Compounds, 3-Ring, Compounds used in a research, industrial, or household setting4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-Dimethylbenzenesulfonamide
go.drugbank.com/drugs/DB01888ExperimentalSynonyms: 4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-Dimethylbenzenesulfonamide4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID
go.drugbank.com/drugs/DB07320ExperimentalSynonyms: 4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACIDMIV-711
go.drugbank.com/drugs/DB15599InvestigationalSynonyms: N-[(2S)-1-[(3aS,6R,6aR)-6-Ethynyl-3-oxohexahydro-2H-furo[3,2-b]pyrrol-4-yl]-4-methyl-1-oxopentan-2-yl]-4-[5-fluoro-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide hydrochlorideFluorocyclopentenylcytosine
go.drugbank.com/drugs/DB16168InvestigationalFluorocyclopentenylcytosine is under investigation in clinical trial NCT03189914 (RX-3117 in Combination With Abraxane® in Subjects With Metastatic Pancreatic Cancer).
Synonyms: 4-amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl) cyclopent-2-en-1-yl] pyrimidin-2-oneCategories: Heterocyclic Compounds, 1-Ring