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Displaying results 2331 - 2340 of 4188 in total
  1. Drug

    Rocaglamide

    go.drugbank.com/drugs/DB15495
    Experimental

    [A186760] Rocaglamides are secondary metabolites of the plant genus _Aglaia_, and extracts of the plant have traditionally been used as a form of insect repellant due to its natural insecticidal properties

  2. Target

    Ferritin

    go.drugbank.com/bio_entities/BE0010292
    CarrierHumans

    Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed:9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed:90031...

    Synonyms: Cell proliferation-inducing gene 15 protein
  3. Drug

    Tagraxofusp

    go.drugbank.com/drugs/DB14731
    ApprovedInvestigational

    Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia co...

  4. Drug

    XEN-D0101

    go.drugbank.com/drugs/DB06020
    Experimental

    XEN-D0101 is an investigational drug developed by Xention Inc. for the treatment of Atrial Fibrillation. XEN-D0101 works by being a selective antagonist of the voltage-gated potassium channel Kv1.5.

  5. Drug

    Sulfamethylthiazole

    go.drugbank.com/drugs/DB15882
    Experimental

    Sulfamethylthiazole is a sulfonamide antibacterial agent.

  6. Drug

    Clinafloxacin

    go.drugbank.com/drugs/DB14025
    Experimental

    It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of serious side effects.

  7. Drug

    Promestriene

    go.drugbank.com/drugs/DB12487
    Investigational

    treating vaginal atrophy symptoms associated with aromatase inhibitor treatment would be precluded if its minimal absorption leads to estrogen-like effects on cell proliferation and estrogen-responsive gene … It has been also studied in phase III of the clinical trial in the post-operative patients with hypospadias.

  8. Drug

    Lanadelumab

    go.drugbank.com/drugs/DB14597
    ApprovedInvestigational

    [L4537] It has been granted priority review, breakthrough therapy, and orphan drug designations for rare diseases based on the results of clinical trials.

  9. Drug

    Succinylcholine

    go.drugbank.com/drugs/DB00202
    ApprovedInvestigational

    [A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures.

  10. Drug

    Hydroquinone

    go.drugbank.com/drugs/DB09526
    ApprovedInvestigational

    As a result of these concerns, hydroquinone has been banned in the EU and UK.