Succinylcholine is a depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter acetylcholine (ACh) linked by their acetyl groups.
- Mechanism
- Curator reviewed · 1 reference
Succinylcholine is a depolarizing neuromuscular blocker, meaning it causes a prolonged period of membrane depolarization in order to exert its therapeutic effects. It binds to the post-synaptic cholinergic receptors found on motor endplates, thereby inducing first transient fasciculations followed by skeletal muscle paralysis.
- Primary indication
- Succinylcholine is indicated as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.Curator reviewed · 2 structured indications
- Formula / weight
- C14H30N2O4 · 290.399 g/mol (avg)
- First approval
- Canada, 2014 · United States, 1952
- Also known as
- Dicholine succinate · Succinocholine · Succinoylcholine · Succinylbischoline · Succinyldicholine
- Brand names
Resolves to
AXOIZCJOOAYSMI-UHFFFAOYSA-NSMILESC[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)CWhat you can answer from here — as of October 01, 2026
Which drugs share a target with Succinylcholine, and which of those have an active Phase 3 trial?
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