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Acenocoumarol
go.drugbank.com/drugs/DB01418ApprovedInvestigationalAcenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and ...
Synonyms: 3-(alpha-Acetonyl-p-nitrobenzyl)-4-hydroxycoumarin, 3-(alpha-(p-Nitrophenol)-beta-acetylethyl)-4-hydroxycoumarinCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesTestosterone propionate
go.drugbank.com/drugs/DB01420ApprovedInvestigationalVet approvedWithdrawnTestosterone propionate is a slower-releasing anabolic steroid with a short half-life. It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone. Testosterone propionate was devel...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesAllylestrenol
go.drugbank.com/drugs/DB01431InvestigationalA synthetic steroid with progestational activity. It is widely marketed throughout Europe, including Russia and many other European countries, and is also available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMidomafetamine
go.drugbank.com/drugs/DB01454IllicitInvestigationalAn N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy. It is a widely abused drug...
Categories: Serotonin Receptor Agonists, Serotonin 5-HT2 Receptor Agonists5-androstenedione
go.drugbank.com/drugs/DB01456ExperimentalIllicit5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its use in athletes is pr...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCathine
go.drugbank.com/drugs/DB01486ExperimentalIllicitCathine, also known as d-norpseudoephedrine and (+)-norpseudoephedrine, is a psychoactive drug with stimulant properties. It belongs to the phenethylamine and amphetamine chemical classes. In the United States, it is classified as a Sche...
Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSulfamethazine
go.drugbank.com/drugs/DB01582ApprovedVet approvedWithdrawnA sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
Synonyms: (p-Aminobenzolsulfonyl)-2-amino-4,6-dimethylpyrimidin, 2-(p-Aminobenzenesulfonamido)-4,6-dimethylpyrimidineEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalEverolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a simi...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesImipenem
go.drugbank.com/drugs/DB01598ApprovedInvestigationalImipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-la...
Tazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationalTazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a vari...
Mixtures: AUROTAZ-P 4.5 G, Aurotaz-P Powder for Injections 4.5 g