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Displaying results 2351 - 2360 of 10000 in total
  1. Target

    Proline dehydrogenase 1, mitochondrial

    go.drugbank.com/bio_entities/BE0002330
    TargetEnzymeHumans

    Converts proline to delta-1-pyrroline-5-carboxylate

    Synonyms: p53-induced gene 6 protein
  2. Target

    Molybdenum cofactor biosynthesis protein 1

    go.drugbank.com/bio_entities/BE0011005
    TargetHumans

    Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP) (PubMed:11891227, PubMed:23627491, PubMed:29368224, PubMed:31996372). MOCS1A catalyzes the cycl...

    Synonyms: Cell migration-inducing gene 11 protein
  3. Target

    Hypoxia-inducible factor 1

    go.drugbank.com/bio_entities/BE0010297
    TargetHumans

    gene promoters (PubMed:28396409, PubMed:34521881). … Forms heterodimers with the aryl hydrocarbon receptor (AHR) to mediate the transcriptional response to xenobiotics by binding xenobiotic response elements (XREs) or dioxin response elements (DREs) in target

    Polypeptides: Aryl hydrocarbon receptor nuclear translocatorSynonyms: Dioxin receptor, nuclear translocator
  4. Drug

    Promestriene

    go.drugbank.com/drugs/DB12487
    Investigational

    Promestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of Hypospadias. It is a synthetic estrogen analog, which is used in topical estrogen therapy. … treating vaginal atrophy symptoms associated with aromatase inhibitor treatment would be precluded if its minimal absorption leads to estrogen-like effects on cell proliferation and estrogen-responsive gene

    Products: ANTROFI®, COLPOTROFINE® CAPSULAS VAGINALES
  5. Target

    Ferritin

    go.drugbank.com/bio_entities/BE0010292
    CarrierHumans

    Delivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron (PubMed:24695223) … Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed:24695223, PubMed:26436293)

    Synonyms: Cell proliferation-inducing gene 15 protein
  6. Drug

    Iferanserin

    go.drugbank.com/drugs/DB11686
    Investigational

    Iferanserin has been investigated for the treatment of Hemorrhoids.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor Antagonists
  7. Drug

    Artefenomel

    go.drugbank.com/drugs/DB11809
    Investigational

    Artefenomel has been investigated for the treatment of Malaria.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  8. Drug

    RO-5028442

    go.drugbank.com/drugs/DB12721
    Investigational

    RO5028442 has been used in trials studying Autistic Disorder.

    Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    ACT-451840

    go.drugbank.com/drugs/DB13054
    Investigational

    ACT-451840 has been used in trials studying Malaria.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Lupeol

    go.drugbank.com/drugs/DB12622
    Investigational

    Lupeol has been investigated for the treatment of Acne.