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Ophthalmia Neonatorum
go.drugbank.com/conditions/DBCOND0000276Drugs: ErythromycinSynonyms: Neonatal conjunctivitis and dacryocystitisUndescended Testis
go.drugbank.com/conditions/DBCOND0033671Synonyms: Undescended and ectopic testicleHyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigationalHyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family. … [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties.
Mixtures: UR N-C Urinary Antiseptic, Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and ButabarbitalCategories: Alimentary Tract and Metabolism, hyoscyamine and psycholepticsSpesolimab
go.drugbank.com/drugs/DB15626ApprovedInvestigational[A252220, A252225] Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved … Spesolimab works by inhibiting the inflammatory signaling pathway of IL-36,[L43090] which is often overexpressed and aberrantly overactive in generalized pustular psoriasis.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsBromotheophylline
go.drugbank.com/drugs/DB14018ApprovedFrom this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. … Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline.
Mixtures: Uphamol Menstrual Tablet 500/25mg, Pain Aid PMFVaborbactam
go.drugbank.com/drugs/DB12107ApprovedInvestigationalVabomere consists of vaborbactam and [Meropenem] for intravenous administration. … [Label] The treatment aims to resolve infection-related symptoms of cUTI and achieve negative urine culture, when the infections are proven or strongly suspected to be caused by susceptible bacteria.
Categories: meropenem and vaborbactamIdebenone
go.drugbank.com/drugs/DB09081ApprovedInvestigationalthe lipid membrane and mitochondria from oxidative damage [A19768]. … It is not currently approved for use by either the Food and Drug Administration (USA) or Health Canada.
Categories: Enzymes and Coenzymes, Psychostimulants, Agents Used for ADHD and NootropicsClostridium tetani toxoid antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10583ApprovedInvestigationalThe toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration and precipation. … It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus.
Mixtures: Diphtheria and Tetanus Toxoids Adsorbed, Tetanus and Diphtheria Toxoids AdsorbedLeniolisib
go.drugbank.com/drugs/DB16217ApprovedInvestigational[L45758] APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby increasing the activity of PI3Kδ, causing immune dysfunction, and elevating susceptibility to infections … Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ).
Categories: Antineoplastic and Immunomodulating AgentsTyphoid Vi polysaccharide vaccine
go.drugbank.com/drugs/DB10803ApprovedInvestigationalIt is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for use in persons two years of age or older. … The bacterial culture is inactivated in the medium with the capsular polysaccharides precipated from the solution.