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Displaying results 231 - 240 of 1186 in total
  1. Target

    Sodium channel protein type 8 subunit alpha

    go.drugbank.com/bio_entities/BE0002084
    TargetHumans

    Pore-forming subunit of a voltage-gated sodium channel complex assuming opened or closed conformations in response to the voltage difference across membranes and through which sodium ions selectively pass along their electrochemical grad...

    Synonyms: MED
  2. Drug

    MP-0250

    go.drugbank.com/drugs/DB17218
    Investigational

    Synonyms: Designed ankyrin repeat protein (MP0250)
  3. Drug

    WT-1 122 long

    go.drugbank.com/drugs/DB17353
    Experimental

    Synonyms: Ser-gly-gln-ala-tyr-met-phe-pro-asn-ala-pro-tyr-leu-pro-ser-cys-leu-glu-ser
  4. Drug

    Factor IX Complex (Human)

    go.drugbank.com/drugs/DB11330
    ApprovedInvestigational

    As the product Kcentra, Factor IX Complex is also indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients

  5. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes [telmisartan], [candesartan], [losartan], [valsartan], and [irbesartan]. … The angiotensin II receptor blocker (ARB) family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized.

    Mixtures: OLMESART MEDO AMLO MY 20/5, OLMESART MEDO AMLO MY 40/5Categories: Angiotensin 2 Receptor Blocker, Angiotensin Receptor Antagonists
  6. Drug

    Efgartigimod alfa

    go.drugbank.com/drugs/DB15270
    ApprovedInvestigational

    Myasthenia gravis (MG) is an autoimmune disorder characterized by significant muscle weakness - particularly in the eye, throat, and extremities - caused by autoantibodies attacking the neuromuscular junction … Efgartigimod alfa for intravenous use was granted FDA approval on December 17, 2021[L39501] and European Commission approval on August 11, 2022 for use in patients with myasthenia gravis.

    Categories: Neonatal Fc Receptor Blocker
  7. Drug

    PMC-403

    go.drugbank.com/drugs/DB18132
    Investigational

    PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.

    Synonyms: a fully human monoclonal antibody that binds and activates the Tie2 receptor
  8. Drug

    2-Methoxyestradiol

    go.drugbank.com/drugs/DB02342
    Investigational

    2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2...

    Synonyms: 2-ME2
  9. Drug

    Oleic monoethanolamide

    go.drugbank.com/drugs/DB16495
    Investigational

    Synonyms: Oleamide MEACategories: Cannabinoid Receptor Agonists
  10. Drug

    WT-1 331 long

    go.drugbank.com/drugs/DB17355
    Experimental

    Synonyms: Pro-gly-cys-asn-lys-arg-tyr-phe-lys-leu-ser-his-leu-gln-met-his-ser-arg-lys-his-thr-gly