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Displaying results 231 - 240 of 10000 in total
  1. Drug

    Diltiazem

    go.drugbank.com/drugs/DB00343
    ApprovedInvestigational

    Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. … [T28] Being a potent vasodilator, diltiazem is used clinically as an antihypertensive, anti-arrhythmic, and as an anti-anginal agent [L6289] for the management of cardiovascular conditions such as hypertension

    Products: Cardizem LA, Matzim LA
  2. Drug

    Hydrocodone

    go.drugbank.com/drugs/DB00956
    ApprovedIllicitInvestigational

    Hydrocodone is a synthetic opioid derivative of codeine.[T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain. … Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by [dextromethorphan] in current cough and cold formulations.

    Mixtures: Vicodin ES, Vicodin ESProducts: Vantrela ER, Hysingla ER
  3. Drug

    Synthetic camphor

    go.drugbank.com/drugs/DB14156
    Approved

    Mixtures: La Vaquita, La Vaquita Extra StrengthProducts: De La Cruz Camphor, De La Cruz Camphorated Alcohol
  4. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907] … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta.

    Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: PEMETREXED EG, Pemetrexed Actavis 100 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  5. Drug

    Tiopronin

    go.drugbank.com/drugs/DB06823
    Approved

    Tiopronin is used as a second-line therapy to control the rate of cystine precipitation and excretion, and prevent kidney stone formation. … It is used after a failure of the non-pharmacological first line treatment consisting of increased fluid intake, restriction of sodium and protein, and urinary alkalinization.

    International brands: Kai NaCategories: N-substituted Glycines
  6. Drug

    Oxybutynin

    go.drugbank.com/drugs/DB01062
    ApprovedInvestigational

    It is often used as first-line therapy for OAB.[A185990] … efficacy since initial FDA approval in 1975.

    Products: OXIBUTININA EG, Pat-oxybutynin Chloride ER
  7. Drug

    Hexetidine

    go.drugbank.com/drugs/DB08958
    ApprovedWithdrawn

    A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.

    Products: BUCOSEPT (SOLUCION ANTISEPTICA Y DESODORANTE PARA LA HIGIENE BUCAL ).
  8. Drug

    Hepatitis A Vaccine

    go.drugbank.com/drugs/DB10989
    ApprovedInvestigational

    [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392] … [A199182] Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been formulated for immunization against hepatitis A virus (HAV) infection and safely confers strong protection

    Synonyms: Hepatitis A Vaccine, Hepatitis A vaccine, inactivatedSalts: Hepatitis A virus strain CR 326F antigen (formaldehyde inactivated), Hepatitis A virus strain HM175 antigen (formaldehyde inactivated)
  9. Target

    Homeobox protein engrailed-2

    go.drugbank.com/bio_entities/BE0004484
    TargetHumans

    Synonyms: Hu-En-2, Homeobox protein en-2
  10. Drug

    Levosimendan

    go.drugbank.com/drugs/DB00922
    ApprovedInvestigationalWithdrawn

    Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. … Levosimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).

    Categories: Compounds used in a research, industrial, or household settingProducts: LEVOSIMENDAN EG, Levosimendan Carinopharm 12,5 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung