Synthetic camphor

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Anbesol Cold Sore Therapy, Flexall Ultra Plus, Icy Hot Arthritis, Ivy-dry Cream, Jointflex, Men-phor, Ortho-nesic, Salonpas Pain Relieving Patch, Tiger Balm, Vaporex, Vicks Vaporub, Vicks Vaposteam
Generic Name
Synthetic camphor
DrugBank Accession Number
DB14156
Background

Not Available

Type
Small Molecule
Groups
Approved, Experimental
Structure
Thumb
Weight
Average: 152.2334
Monoisotopic: 152.120115134
Chemical Formula
C10H16O
Synonyms
  • (+/-)-camphor
  • (1RS,4RS)-1,7,7-trimethylbicyclo(2.2.1)heptan-2-one
  • 1,7,7-trimethylbicyclo(2.2.1)heptan-2-one
  • 2-bornanone
  • 2-camphanone
  • Camphor (synthetic)
  • Camphor, racemic
  • DL-camphor
  • Gum camphor
External IDs
  • Fema no. 4513

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

Products
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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
ALLG Essentials Warm-up AcceleratorCream5 mg/100gTopicalGlobal Products Group, LLC2019-03-15Not applicableUS flag
AllG Pain Relief Fast Acting PainCream5 mg/100gTopicalGlobal Products Group, LLC2020-09-28Not applicableUS flag
Apanol AlcanforOintment10 g/100gTopicalDelon Laboratories (1990) Ltd.2010-11-192014-12-03US flag
Arthritis and Joint Pain Relief ThayersGel3 g/100mLTopicalProduct Quest Mfg.2016-03-012017-12-26US flag
Arthro Pharma Pain ReliefGel30 mg/1mLTopicalJajy Ventures, Llc2016-11-01Not applicableUS flag
Best Choice Vapor SteamLiquid0.623 g/10mLRespiratory (inhalation)Valu merchandiser2011-11-02Not applicableUS flag
Blue Star MedicatedOintment1.24 g/100gTopicalFocus Consumer Healthcare, Llc2017-10-13Not applicableUS flag
CamphorLiquid155 mg/1mLRespiratory (inhalation)CVS Health2009-05-19Not applicableUS flag
CbdCream5 mg/100gTopicalSmartScience Laboratories, Inc.2020-02-12Not applicableUS flag
CBD Clinic - Massage Oil - Level 1Oil0.03 kg/1kgTopicalAidance Skincare & Topical Solutions, LLC2017-05-15Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
4oz Medicated Chest RubSynthetic camphor (4.7 g/100g) + Eucalyptus oil (1 g/100g) + Levomenthol (1 g/100g)OintmentTopicalPride Products Corporation2017-12-01Not applicableUS flag
701 Dieda Zhengtong Yaogao MedicatedSynthetic camphor (3.1 g/1) + Levomenthol (8 g/1) + Methyl salicylate (10 g/1)PlasterTopical; TransdermalGUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO., LTD. BAIYUNSHAN HEJIGONG PHARMACEUTICAL FACTORY2001-10-15Not applicableUS flag
701 Dieda Zhengtong Yaogao MedicatedSynthetic camphor (3.1 g/100g) + Levomenthol (5 g/100g)PlasterTransdermalMadison One Acme Inc2020-05-04Not applicableUS flag
999 Itch ReliefSynthetic camphor (200 mg/20000mg) + Dexamethasone (15 mg/20000mg) + Levomenthol (200 mg/20000mg)OintmentTopicalChina Resources Sanjiu Medical & Pharmaceutical Co., Ltd.2003-07-03Not applicableUS flag
ACTIBEAU Sports MassageSynthetic camphor (0.6 g/120g) + Levomenthol (4.2 g/120g)GelTopicalACTIVEBEUTY CO.,LTD.2019-04-01Not applicableUS flag
AI TapeSynthetic camphor (3 g/100g) + Levomenthol (7 g/100g)TapeTopicalActive Intelligence, Llc2017-03-01Not applicableUS flag
Air Sinsin PasSynthetic camphor (0.361 g/100mL) + Levomenthol (0.289 g/100mL) + Methyl salicylate (0.361 g/100mL)Aerosol, sprayCutaneous; Topical; TransdermalSinsin Pharmaceutical Co., Ltd.2011-07-01Not applicableUS flag
Air Sinsinpas-EXSynthetic camphor (6 g/200mL) + Levomenthol (6.4 g/200mL) + Methyl salicylate (3.5 g/200mL)SprayTopicalSinsin Pharmaceutical Co., Ltd.2017-08-22Not applicableUS flag
Allure Ice Cold AnalgesicSynthetic camphor (0.5 g/100g) + Levomenthol (1 g/100g)GelTopicalUniversal Distribution Center LLC2012-06-30Not applicableUS flag
Allure Vaporizing Chest RubSynthetic camphor (4.7 g/100g) + Eucalyptus oil (1.0 g/100g) + Levomenthol (1.0 g/100g)GelTopicalUniversal Distribution Center LLC2012-06-30Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Antiphlamine Coin PlasterSynthetic camphor (1.108 mg/0.2832g) + Diphenhydramine (0.246 mg/0.2832g) + Levomenthol (2.769 mg/0.2832g)PatchTopicalHanul Trading Co., Ltd.2016-10-102017-04-14US flag
Antiphlamine Coin PlasterSynthetic camphor (1.108 mg/0.2832g) + DL-alpha-Tocopherol (0.308 mg/0.2832g) + Diphenhydramine (0.246 mg/0.2832g) + Levomenthol (2.769 mg/0.2832g) + Methyl salicylate (5.541 mg/0.2832g) + Nonivamide (0.046 mg/0.2832g) + Peppermint oil (0.693 mg/0.2832g)PatchTopicalHanul Trading Co., Ltd.2016-10-10Not applicableUS flag
CoreTex Professional Outdoor Skin Protection WalletSynthetic camphor (0.1 g/100mL) + Avobenzone (1 g/100mL) + Avobenzone (1 g/100g) + Avobenzone (3 g/100mL) + Benzocaine (6 g/100mL) + Diphenhydramine hydrochloride (2 g/100mL) + Ethanol (62.5 mL/100mL) + Homosalate (5 g/100mL) + Homosalate (5 g/100g) + Homosalate (7.5 g/100mL) + Octinoxate (7.5 g/100mL) + Octinoxate (7.5 g/100g) + Octisalate (5 g/100mL) + Octisalate (5 g/100g) + Octisalate (5 g/100mL) + Octocrylene (2.5 g/100mL) + Oxybenzone (6 g/100mL) + Oxybenzone (6 g/100g) + Oxybenzone (6 g/100mL) + Zinc acetate dihydrate (1 g/100mL)TopicalCoreTex Products2019-11-27Not applicableUS flag
DiclotrexSynthetic camphor (4 g/100g) + Diclofenac sodium (16.05 mg/1mL) + Levomenthol (10 g/100g)KitTopicalPureTek Corporation2018-10-23Not applicableUS flag
Pain ReliefRoll On Roll OnSynthetic camphor (2.8 g/70g) + Levomenthol (7 g/70g) + Methyl salicylate (21 g/70g)LiquidTopicalCreations Garden Natural Products2010-03-10Not applicableUS flag
Pain Relieving Ultra StrengthSynthetic camphor (2.28 g/57g) + Levomenthol (5.7 g/57g) + Methyl salicylate (9 g/57g)CreamTopicalCreations Garden Natural Products2010-03-31Not applicableUS flag
Preferred Plus Medicated Lip BalmSynthetic camphor (17 mg/1g) + Levomenthol (7 mg/1g) + Phenol (4 mg/1g)StickTopicalKinray2007-02-28Not applicableUS flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Not Available
CAS number
76-22-2
InChI Key
DSSYKIVIOFKYAU-UHFFFAOYSA-N
InChI
InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3
IUPAC Name
1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
SMILES
CC1(C)C2CCC1(C)C(=O)C2

References

General References
Not Available
KEGG Compound
C18369
ChemSpider
2441
RxNav
1371994
ChEBI
36773
ChEMBL
CHEMBL15768

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
TapeTopical
Aerosol, sprayCutaneous; Topical; Transdermal
CreamTopical5 mg/100g
LotionTopical
OintmentTopical10 g/100g
GelTopical3 g/100mL
GelTopical30 mg/1mL
OilPercutaneous; Topical; Transdermal
PasteTopical
OintmentTopical1.24 g/100g
LiquidRespiratory (inhalation)155 mg/1mL
OintmentRespiratory (inhalation)
GelTopical
OintmentTopical
OilTopical0.03 kg/1kg
CreamTopical3 g/100g
GelTopical4.5 mg/1g
OintmentTopical0.6 g/100g
GelTransdermal
LotionRespiratory (inhalation)
LiquidRespiratory (inhalation)0.623 g/10mL
LiquidTopical110 mg/1mL
ShampooTopical0.001 g/100mL
KitTopical
LinimentTopical
PlasterTopical; Transdermal
PatchCutaneous; Topical; Transdermal
CreamTopical50 mg/1mL
SuppositoryRectal0.025 g/1g
PlasterTopical
KitOral; Topical
SprayTopical
PlasterTransdermal3 g/100g
CreamTopical3.18 g/100g
CreamTopical3.2 g/100g
CreamTopical3.58 g/114g
CreamTopical31 mg/1g
StickTopical
JellyTopical
SolutionTopical
CreamTopical
OintmentTopical4 g/100g
ClothTopical1 mL/1
SprayTopical1 mL/30mL
LiquidTopical0.0198 g/1g
TinctureTopical
LiquidTopical
PatchTopical
CreamCutaneous; Topical
OintmentCutaneous; Topical
GelCutaneous; Topical
PlasterTopical3 1/1001
PatchPercutaneous; Topical; Transdermal
LiquidRespiratory (inhalation)6.2 g/118mL
SolutionCutaneous
PatchTopical0.13 g/100g
GelPercutaneous; Topical; Transdermal
LiquidRespiratory (inhalation).623 g/10mL
PlasterTransdermal
LiquidCutaneous; Topical; Transdermal
PatchTransdermal
SalveTopical
LiquidRespiratory (inhalation)0.062 g/1mL
OilTransdermal
OilTopical
SolutionNasal
OilTopical4 g/100mL
LinimentPercutaneous; Transdermal
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.88 mg/mLALOGPS
logP2.85ALOGPS
logP2.55ChemAxon
logS-2.2ALOGPS
pKa (Strongest Basic)-7.5ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area17.07 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity44.49 m3·mol-1ChemAxon
Polarizability17.74 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created on June 29, 2018 14:55 / Updated on June 12, 2020 16:53