Synthetic camphor

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Anbesol Cold Sore Therapy, Flexall Ultra Plus, Icy Hot Arthritis, Ivy-dry Cream, Jointflex, Men-phor, Ortho-nesic, Salonpas Pain Relieving Patch, Sarna Sensitive, Tiger Balm, Vaporex, Vicks Vaporub, Vicks Vaposteam
Generic Name
Synthetic camphor
DrugBank Accession Number
DB14156
Background

Not Available

Type
Small Molecule
Groups
Approved, Experimental
Structure
Weight
Average: 152.2334
Monoisotopic: 152.120115134
Chemical Formula
C10H16O
Synonyms
  • (+/-)-camphor
  • (1RS,4RS)-1,7,7-trimethylbicyclo(2.2.1)heptan-2-one
  • 1,7,7-trimethylbicyclo(2.2.1)heptan-2-one
  • 2-bornanone
  • 2-camphanone
  • Camphor (synthetic)
  • Camphor, racemic
  • DL-camphor
  • Gum camphor
External IDs
  • Fema no. 4513

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatBack pain lower backCombination Product in combination with: Glycol salicylate (DB11323), Nonivamide (DB11324), Levomenthol (DB00825)••• •••••••••
Used in combination for symptomatic treatment ofBack pain, unspecifiedCombination Product in combination with: Levomenthol (DB00825), Capsicum (DB10897), Eucalyptus oil (DB11114), Mentha arvensis leaf oil (DB16575)•••••••••••••••••
Used in combination to treatBruisesCombination Product in combination with: Glycol salicylate (DB11323), Levomenthol (DB00825), Nonivamide (DB11324)••• •••••••••
Symptomatic treatment ofItch••• •••
Used in combination to treatJoint painCombination Product in combination with: Levomenthol (DB00825), Glycol salicylate (DB11323), Nonivamide (DB11324)••• •••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
ALLG Essentials Warm-up AcceleratorCream5 mg/100gTopicalGlobal Products Group, LLC2019-03-15Not applicableUS flag
AllG Pain Relief Fast Acting PainCream5 mg/100gTopicalGlobal Products Group, LLC2020-09-28Not applicableUS flag
Apanol AlcanforOintment10 g/100gTopicalDelon Laboratories (1990) Ltd.2010-11-192014-12-03US flag
Arthritis and Joint Pain Relief ThayersGel3 g/100mLTopicalProduct Quest Mfg.2016-03-012017-12-26US flag
Arthro Pharma Pain ReliefGel30 mg/1mLTopicalJajy Ventures, Llc2016-11-01Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
24/7 Life Medicated Chest RubSynthetic camphor (4.8 g/100g) + Eucalyptus oil (1.2 g/100g) + Menthol (2.6 g/100g)OintmentTopicalLil' Drug Store Products, Inc.2022-11-11Not applicableUS flag
4oz Medicated Chest RubSynthetic camphor (4.7 g/100g) + Eucalyptus oil (1 g/100g) + Menthol (1 g/100g)OintmentTopicalPride Products Corporation2017-12-01Not applicableUS flag
701 Dieda Zhengtong Yaogao MedicatedSynthetic camphor (3.1 g/1) + Menthol (8 g/1) + Methyl salicylate (10 g/1)PlasterTopical; TransdermalGUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO., LTD. BAIYUNSHAN HEJIGONG PHARMACEUTICAL FACTORY2001-10-15Not applicableUS flag
701 Dieda Zhengtong Yaogao MedicatedSynthetic camphor (3.1 g/100g) + Menthol (5 g/100g)PlasterTransdermalMadison One Acme Inc2020-05-04Not applicableUS flag
7th MANNA PAIN RELIEF DROPSSynthetic camphor (30 mg/1mL) + Menthol (100 mg/1mL)LiquidTopical7TH MANNA (USA) PTE. LTD.2023-09-25Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Antiphlamine Coin PlasterSynthetic camphor (1.108 mg/0.2832g) + Diphenhydramine (0.246 mg/0.2832g) + Levomenthol (2.769 mg/0.2832g)PatchTopicalHanul Trading Co., Ltd.2016-10-102017-04-14US flag
Antiphlamine Coin PlasterSynthetic camphor (1.108 mg/0.2832g) + DL-alpha-Tocopherol (0.308 mg/0.2832g) + Diphenhydramine (0.246 mg/0.2832g) + Levomenthol (2.769 mg/0.2832g) + Methyl salicylate (5.541 mg/0.2832g) + Nonivamide (0.046 mg/0.2832g) + Peppermint oil (0.693 mg/0.2832g)PatchTopicalHanul Trading Co., Ltd.2016-10-10Not applicableUS flag
CoreTex Professional Outdoor Skin Protection WalletSynthetic camphor (0.1 g/100mL) + Avobenzone (1 g/100mL) + Avobenzone (1 g/100g) + Avobenzone (3 g/100mL) + Benzocaine (6 g/100mL) + Diphenhydramine hydrochloride (2 g/100mL) + Ethanol (62.5 mL/100mL) + Homosalate (5 g/100mL) + Homosalate (5 g/100g) + Homosalate (7.5 g/100mL) + Octinoxate (7.5 g/100mL) + Octinoxate (7.5 g/100g) + Octisalate (5 g/100mL) + Octisalate (5 g/100g) + Octisalate (5 g/100mL) + Octocrylene (2.5 g/100mL) + Oxybenzone (6 g/100mL) + Oxybenzone (6 g/100g) + Oxybenzone (6 g/100mL) + Zinc acetate dihydrate (1 g/100mL)Gel; Kit; Lipstick; Liquid; Lotion; SwabTopicalCoreTex Products Inc2019-11-27Not applicableUS flag
DiclotrexSynthetic camphor (4 g/100g) + Diclofenac sodium (16.05 mg/1mL) + Menthol (10 g/100g)KitTopicalPureTek Corporation2018-10-232024-04-30US flag
DiclotrexSynthetic camphor (4 g/100g) + Diclofenac sodium (16.05 mg/1mL) + Menthol (10 g/100g)KitTopicalPureTek Corporation2022-03-022024-04-30US flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
5TJD82A1ET
CAS number
76-22-2
InChI Key
DSSYKIVIOFKYAU-UHFFFAOYSA-N
InChI
InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3
IUPAC Name
1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
SMILES
CC1(C)C2CCC1(C)C(=O)C2

References

General References
Not Available
KEGG Compound
C18369
ChemSpider
2441
RxNav
1371994
ChEBI
36773
ChEMBL
CHEMBL15768

Clinical Trials

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Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
TapeTopical
Aerosol, sprayCutaneous; Topical; Transdermal
SprayTopical
CreamTopical5 mg/100g
LotionTopical
OintmentTopical10 g/100g
GelTopical3 g/100mL
GelTopical30 mg/1mL
OilPercutaneous; Topical; Transdermal
KitTopical
PasteTopical
Kit; ointment; stickTopical
OintmentTopical1.24 g/100g
LiquidRespiratory (inhalation)155 mg/1mL
GelTopical
OintmentRespiratory (inhalation)
SalveTopical
OilTopical0.03 kg/1kg
CreamTopical3 g/100g
GelTopical4.5 mg/1g
OintmentTopical0.6 g/100g
SolutionTopical
GelTransdermal
PatchTransdermal
OintmentTopical
Gel; kit; lipstick; liquid; lotion; swabTopical
LotionRespiratory (inhalation)
LiquidRespiratory (inhalation)0.623 g/10mL
OintmentTopical11 g/100g
LiquidTopical110 mg/1mL
ShampooTopical0.001 g/100mL
LinimentTopical
SolutionTopical17.326 mg/.55mL
LiquidRespiratory (inhalation)6.23 g/10mL
PlasterTopical; Transdermal
PatchCutaneous; Topical; Transdermal
CreamTopical50 mg/1mL
SuppositoryRectal0.025 g/1g
PlasterTopical
OilTopical
Gel; kit; tablet, delayed releaseOral; Topical
PlasterTransdermal3 g/100g
CreamTopical3.18 g/100g
CreamTopical3.2 g/100g
CreamTopical3.58 g/114g
CreamTopical31 mg/1g
Kit; liquid; ointmentBuccal; Topical
LiquidTopical
JellyTopical
Gel; kit; tabletOral; Topical
GelTopical0.33 g/100mL
OintmentTopical4 g/100g
ClothTopical1 mL/1
SprayTopical1 mL/30mL
LiquidTopical0.0198 g/1g
TinctureTopical
PatchTopical
StickTopical
CreamCutaneous; Topical
OintmentCutaneous; Topical
GelCutaneous; Topical
PlasterTopical3 1/1001
PatchPercutaneous; Topical; Transdermal
LiquidRespiratory (inhalation)6.2 g/118mL
SolutionCutaneous
PatchTopical0.13 g/100g
GelPercutaneous; Topical; Transdermal
GelTopical1 g/100mL
LiquidRespiratory (inhalation).623 g/10mL
CreamTopical
LiquidCutaneous; Topical; Transdermal
GelTopical0.03 g/1g
PlasterTransdermal
LinimentPercutaneous
InhalantRespiratory (inhalation)62 mg/1mL
LiquidRespiratory (inhalation)0.062 g/1mL
OilTransdermal
SolutionNasal
OilTopical4 g/100mL
LinimentPercutaneous; Transdermal
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.88 mg/mLALOGPS
logP2.85ALOGPS
logP2.55Chemaxon
logS-2.2ALOGPS
pKa (Strongest Basic)-7.5Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area17.07 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity44.49 m3·mol-1Chemaxon
Polarizability17.74 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0900000000-f988c217c33c41bd9884
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4i-0900000000-5128b8f555a7e82225a7
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0900000000-a77c45fae32da597897d
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a6r-2900000000-d1f2122565c9f9eae861
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0900000000-bcc7bae1dc5deb7796d7
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-002f-9300000000-b84a02be1ab328f87f8f
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-131.3064868
predicted
DarkChem Lite v0.1.0
[M-H]-139.03908
predicted
DeepCCS 1.0 (2019)
[M+H]+130.3951568
predicted
DarkChem Standard v0.1.0
[M+H]+142.24402
predicted
DeepCCS 1.0 (2019)
[M+Na]+131.6896868
predicted
DarkChem Lite v0.1.0
[M+Na]+151.407
predicted
DeepCCS 1.0 (2019)

Drug created at June 29, 2018 14:55 / Updated at September 28, 2021 21:54