Synthetic camphor
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Brand Names
- Anbesol Cold Sore Therapy, Flexall Ultra Plus, Icy Hot Arthritis, Ivy-dry Cream, Jointflex, Men-phor, Ortho-nesic, Salonpas Pain Relieving Patch, Sarna Sensitive, Tiger Balm, Vaporex, Vicks Vaporub, Vicks Vaposteam
- Generic Name
- Synthetic camphor
- DrugBank Accession Number
- DB14156
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Structure
- Weight
- Average: 152.2334
Monoisotopic: 152.120115134 - Chemical Formula
- C10H16O
- Synonyms
- (+/-)-camphor
- (1RS,4RS)-1,7,7-trimethylbicyclo(2.2.1)heptan-2-one
- 1,7,7-trimethylbicyclo(2.2.1)heptan-2-one
- 2-bornanone
- 2-camphanone
- Camphor (synthetic)
- Camphor, racemic
- DL-camphor
- Gum camphor
- External IDs
- Fema no. 4513
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to treat Back pain lower back Combination Product in combination with: Glycol salicylate (DB11323), Nonivamide (DB11324), Levomenthol (DB00825) ••• ••• •••••• Used in combination for symptomatic treatment of Back pain, unspecified Combination Product in combination with: Levomenthol (DB00825), Capsicum (DB10897), Eucalyptus oil (DB11114), Mentha arvensis leaf oil (DB16575) •••••••••••• ••••• Used in combination to treat Bruises Combination Product in combination with: Glycol salicylate (DB11323), Levomenthol (DB00825), Nonivamide (DB11324) ••• ••• •••••• Symptomatic treatment of Itch ••• ••• Used in combination to treat Joint pain Combination Product in combination with: Levomenthol (DB00825), Glycol salicylate (DB11323), Nonivamide (DB11324) ••• ••• •••••• - Contraindications & Blackbox Warnings
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image ALLG Essentials Warm-up Accelerator Cream 5 mg/100g Topical Global Products Group, LLC 2019-03-15 Not applicable US AllG Pain Relief Fast Acting Pain Cream 5 mg/100g Topical Global Products Group, LLC 2020-09-28 Not applicable US Apanol Alcanfor Ointment 10 g/100g Topical Delon Laboratories (1990) Ltd. 2010-11-19 2014-12-03 US Arthritis and Joint Pain Relief Thayers Gel 3 g/100mL Topical Product Quest Mfg. 2016-03-01 2017-12-26 US Arthro Pharma Pain Relief Gel 30 mg/1mL Topical Jajy Ventures, Llc 2016-11-01 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 24/7 Life Medicated Chest Rub Synthetic camphor (4.8 g/100g) + Eucalyptus oil (1.2 g/100g) + Menthol (2.6 g/100g) Ointment Topical Lil' Drug Store Products, Inc. 2022-11-11 Not applicable US 4oz Medicated Chest Rub Synthetic camphor (4.7 g/100g) + Eucalyptus oil (1 g/100g) + Menthol (1 g/100g) Ointment Topical Pride Products Corp. 2017-12-01 Not applicable US 701 Dieda Zhengtong Yaogao Medicated Synthetic camphor (3.1 g/1) + Menthol (8 g/1) + Methyl salicylate (10 g/1) Plaster Topical; Transdermal GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO., LTD. BAIYUNSHAN HEJIGONG PHARMACEUTICAL FACTORY 2001-10-15 Not applicable US 701 Dieda Zhengtong Yaogao Medicated Synthetic camphor (3.1 g/100g) + Menthol (5 g/100g) Plaster Transdermal Madison One Acme Inc 2020-05-04 Not applicable US 7th MANNA PAIN RELIEF DROPS Synthetic camphor (30 mg/1mL) + Menthol (100 mg/1mL) Liquid Topical 7TH MANNA (USA) PTE. LTD. 2023-09-25 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Antiphlamine Coin Plaster Synthetic camphor (1.108 mg/0.2832g) + DL-alpha-Tocopherol (0.308 mg/0.2832g) + Diphenhydramine (0.246 mg/0.2832g) + Levomenthol (2.769 mg/0.2832g) + Methyl salicylate (5.541 mg/0.2832g) + Nonivamide (0.046 mg/0.2832g) + Peppermint oil (0.693 mg/0.2832g) Patch Topical Hanul Trading Co., Ltd. 2016-10-10 Not applicable US Antiphlamine Coin Plaster Synthetic camphor (1.108 mg/0.2832g) + Diphenhydramine (0.246 mg/0.2832g) + Levomenthol (2.769 mg/0.2832g) Patch Topical Hanul Trading Co., Ltd. 2016-10-10 2017-04-14 US CoreTex Professional Outdoor Skin Protection Wallet Synthetic camphor (0.1 g/100mL) + Avobenzone (1 g/100mL) + Avobenzone (1 g/100g) + Avobenzone (3 g/100mL) + Benzocaine (6 g/100mL) + Diphenhydramine hydrochloride (2 g/100mL) + Ethanol (62.5 mL/100mL) + Homosalate (5 g/100mL) + Homosalate (5 g/100g) + Homosalate (7.5 g/100mL) + Octinoxate (7.5 g/100mL) + Octinoxate (7.5 g/100g) + Octisalate (5 g/100mL) + Octisalate (5 g/100g) + Octisalate (5 g/100mL) + Octocrylene (2.5 g/100mL) + Oxybenzone (6 g/100mL) + Oxybenzone (6 g/100g) + Oxybenzone (6 g/100mL) + Zinc acetate dihydrate (1 g/100mL) Gel; Kit; Lipstick; Liquid; Lotion; Swab Topical CoreTex Products Inc 2019-11-27 Not applicable US Diclogen Synthetic camphor (4 g/100g) + Diclofenac sodium (16.05 mg/1mL) + Menthol (10 g/100g) Gel; Kit; Solution Topical PureTek Corporation 2024-07-26 Not applicable US Diclotrex Synthetic camphor (4 g/100g) + Diclofenac sodium (16.05 mg/1mL) + Menthol (10 g/100g) Kit Topical PureTek Corporation 2018-10-23 2024-04-30 US
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 5TJD82A1ET
- CAS number
- 76-22-2
- InChI Key
- DSSYKIVIOFKYAU-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3
- IUPAC Name
- 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
- SMILES
- CC1(C)C2CCC1(C)C(=O)C2
References
- General References
- Not Available
- External Links
- KEGG Compound
- C18369
- ChemSpider
- 2441
- 1371994
- ChEBI
- 36773
- ChEMBL
- CHEMBL15768
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tape Topical Aerosol, spray Cutaneous; Topical; Transdermal Spray Topical Cream Topical 5 mg/100g Lotion Topical Ointment Topical 10 g/100g Gel Topical 3 g/100mL Gel Topical 30 mg/1mL Oil Percutaneous; Topical; Transdermal Kit Topical Paste Topical Kit; ointment; stick Topical Ointment Topical 1.24 g/100g Liquid Respiratory (inhalation) 155 mg/1mL Gel Topical Ointment Respiratory (inhalation) Salve Topical Oil Topical 0.03 kg/1kg Cream Topical 3 g/100g Gel Topical 4.5 mg/1g Ointment Topical 0.6 g/100g Solution Topical Gel Transdermal Patch Transdermal Ointment Topical Gel; kit; lipstick; liquid; lotion; swab Topical Lotion Respiratory (inhalation) Liquid Respiratory (inhalation) 0.623 g/10mL Ointment Topical 11 g/100g Liquid Topical 110 mg/1mL Shampoo Topical 0.001 g/100mL Gel; kit; solution Topical Liniment Topical Solution Topical 17.326 mg/.55mL Liquid Respiratory (inhalation) 6.23 g/10mL Plaster Topical; Transdermal Patch Cutaneous; Topical; Transdermal Cream Topical 50 mg/1mL Suppository Rectal 0.025 g/1g Plaster Topical Oil Topical Gel; kit; tablet, delayed release Oral; Topical Plaster Transdermal 3 g/100g Cream Topical 3.18 g/100g Cream Topical 3.2 g/100g Cream Topical 3.58 g/114g Cream Topical 31 mg/1g Kit; liquid; ointment Buccal; Topical Liquid Topical Jelly Topical Gel; kit; tablet Oral; Topical Gel Topical 0.33 g/100mL Ointment Topical 4 g/100g Cloth Topical 1 mL/1 Spray Topical 1 mL/30mL Liquid Topical 0.0198 g/1g Tincture Topical Patch Topical Stick Topical Cream Cutaneous; Topical Ointment Cutaneous; Topical Gel Cutaneous; Topical Plaster Topical 3 1/1001 Patch Percutaneous; Topical; Transdermal Liquid Respiratory (inhalation) 6.2 g/118mL Solution Cutaneous Patch Topical 0.13 g/100g Gel Percutaneous; Topical; Transdermal Gel Topical 1 g/100mL Liquid Respiratory (inhalation) .623 g/10mL Cream Topical Liquid Cutaneous; Topical; Transdermal Gel Topical 0.03 g/1g Plaster Transdermal Liniment Percutaneous Inhalant Respiratory (inhalation) 62 mg/1mL Liquid Respiratory (inhalation) 0.062 g/1mL Oil Transdermal Solution Nasal Oil Topical 4 g/100mL Liniment Percutaneous; Transdermal - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.88 mg/mL ALOGPS logP 2.85 ALOGPS logP 2.55 Chemaxon logS -2.2 ALOGPS pKa (Strongest Basic) -7.5 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 17.07 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 44.49 m3·mol-1 Chemaxon Polarizability 17.74 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0udi-0900000000-f988c217c33c41bd9884 Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-0a4i-0900000000-5128b8f555a7e82225a7 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-0udi-0900000000-a77c45fae32da597897d Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-0a6r-2900000000-d1f2122565c9f9eae861 Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-0udi-0900000000-bcc7bae1dc5deb7796d7 Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-002f-9300000000-b84a02be1ab328f87f8f Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 131.3064868 predictedDarkChem Lite v0.1.0 [M-H]- 139.03908 predictedDeepCCS 1.0 (2019) [M+H]+ 130.3951568 predictedDarkChem Standard v0.1.0 [M+H]+ 142.24402 predictedDeepCCS 1.0 (2019) [M+Na]+ 131.6896868 predictedDarkChem Lite v0.1.0 [M+Na]+ 151.407 predictedDeepCCS 1.0 (2019)
Drug created at June 29, 2018 14:55 / Updated at September 28, 2021 21:54