Synthetic camphor

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names

Anbesol Cold Sore Therapy, Flexall Ultra Plus, Icy Hot Arthritis, Ivy-dry Cream, Jointflex, Men-phor, Ortho-nesic, Salonpas Pain Relieving Patch, Sarna Sensitive, Tiger Balm, Vaporex, Vicks Vaporub, Vicks Vaposteam

Generic Name

Synthetic camphor

DrugBank Accession Number

DB14156

Background

Not Available

Type

Small Molecule

Groups

Approved, Experimental

Structure

Similar Structures

Weight: Average: 152.2334
Monoisotopic: 152.120115134
Chemical Formula: C₁₀H₁₆O

Synonyms

(+/-)-camphor
(1RS,4RS)-1,7,7-trimethylbicyclo(2.2.1)heptan-2-one
1,7,7-trimethylbicyclo(2.2.1)heptan-2-one
2-bornanone
2-camphanone
Camphor (synthetic)
Camphor, racemic
DL-camphor
Gum camphor

External IDs

Fema no. 4513

Pharmacology

Indication

Not Available

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Associated Conditions

Contraindications & Blackbox Warnings

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Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

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Toxicity

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: No interactions found.

Products

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Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End
ALLG Essentials Warm-up Accelerator	Cream	5 mg/100g	Topical	Global Products Group, LLC	2019-03-15	Not applicable
AllG Pain Relief Fast Acting Pain	Cream	5 mg/100g	Topical	Global Products Group, LLC	2020-09-28	Not applicable
Apanol Alcanfor	Ointment	10 g/100g	Topical	Delon Laboratories (1990) Ltd.	2010-11-19	2014-12-03
Arthritis and Joint Pain Relief Thayers	Gel	3 g/100mL	Topical	Product Quest Mfg.	2016-03-01	2017-12-26
Arthro Pharma Pain Relief	Gel	30 mg/1mL	Topical	Jajy Ventures, Llc	2016-11-01	Not applicable
Best Choice Vapor Steam	Liquid	0.623 g/10mL	Respiratory (inhalation)	Valu merchandiser	2011-11-02	Not applicable
Blue Star Medicated	Ointment	1.24 g/100g	Topical	Focus Consumer Healthcare, Llc	2017-10-13	Not applicable
Camphor	Liquid	155 mg/1mL	Respiratory (inhalation)	CVS Health	2009-05-19	Not applicable
Cbd	Cream	5 mg/100g	Topical	SmartScience Laboratories, Inc.	2020-02-12	Not applicable
CBD Clinic - Massage Oil - Level 1	Oil	0.03 kg/1kg	Topical	Aidance Skincare & Topical Solutions, LLC	2017-05-15	Not applicable

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
4oz Medicated Chest Rub	Synthetic camphor (4.7 g/100g) + Eucalyptus oil (1 g/100g) + Menthol (1 g/100g)	Ointment	Topical	Pride Products Corporation	2017-12-01	Not applicable
701 Dieda Zhengtong Yaogao Medicated	Synthetic camphor (3.1 g/100g) + Menthol (5 g/100g)	Plaster	Transdermal	Madison One Acme Inc	2020-05-04	Not applicable
701 Dieda Zhengtong Yaogao Medicated	Synthetic camphor (3.1 g/1) + Menthol (8 g/1) + Methyl salicylate (10 g/1)	Plaster	Topical; Transdermal	GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO., LTD. BAIYUNSHAN HEJIGONG PHARMACEUTICAL FACTORY	2001-10-15	Not applicable
999 Itch Relief	Synthetic camphor (200 mg/20000mg) + Dexamethasone (15 mg/20000mg) + Menthol (200 mg/20000mg)	Ointment	Topical	China Resources Sanjiu Medical & Pharmaceutical Co Ltd	2003-07-03	Not applicable
Abridge Cold Sore Treatment	Synthetic camphor (30 mg/1g) + Menthol (10 mg/1g) + Petrolatum (892 mg/1g) + Phenol (15 mg/1g)	Cream	Topical	Ranir LLC	2020-02-24	Not applicable
Abridge Cold Sore Treatment	Synthetic camphor (30 mg/1g) + Benzalkonium chloride (1.3 mg/1g)	Cream	Topical	Ranir LLC	2013-04-05	2021-05-12
ABSORBINE jr. PLUS Knee	Synthetic camphor (7 mg/100mg) + Menthol (7 mg/100mg)	Patch	Topical	Clarion Brands, Llc	2022-01-01	Not applicable
ABSORBINE jr. PLUS Pain Relief MICRO	Synthetic camphor (7 mg/100mg) + Menthol (7 mg/100mg)	Patch	Topical	Clarion Brands, Llc	2022-01-01	Not applicable
ACTIBEAU Sports Massage	Synthetic camphor (0.6 g/120g) + Menthol (4.2 g/120g)	Gel	Topical	ACTIVEBEUTY CO.,LTD.	2019-04-01	Not applicable
AI Tape	Synthetic camphor (3 g/100g) + Menthol (7 g/100g)	Tape	Topical	Active Intelligence, Llc	2017-03-01	Not applicable

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
Antiphlamine Coin Plaster	Synthetic camphor (1.108 mg/0.2832g) + DL-alpha-Tocopherol (0.308 mg/0.2832g) + Diphenhydramine (0.246 mg/0.2832g) + Levomenthol (2.769 mg/0.2832g) + Methyl salicylate (5.541 mg/0.2832g) + Nonivamide (0.046 mg/0.2832g) + Peppermint oil (0.693 mg/0.2832g)	Patch	Topical	Hanul Trading Co., Ltd.	2016-10-10	Not applicable
Antiphlamine Coin Plaster	Synthetic camphor (1.108 mg/0.2832g) + Diphenhydramine (0.246 mg/0.2832g) + Levomenthol (2.769 mg/0.2832g)	Patch	Topical	Hanul Trading Co., Ltd.	2016-10-10	2017-04-14
CoreTex Professional Outdoor Skin Protection Wallet	Synthetic camphor (0.1 g/100mL) + Avobenzone (1 g/100mL) + Avobenzone (1 g/100g) + Avobenzone (3 g/100mL) + Benzocaine (6 g/100mL) + Diphenhydramine hydrochloride (2 g/100mL) + Ethanol (62.5 mL/100mL) + Homosalate (5 g/100mL) + Homosalate (5 g/100g) + Homosalate (7.5 g/100mL) + Octinoxate (7.5 g/100mL) + Octinoxate (7.5 g/100g) + Octisalate (5 g/100mL) + Octisalate (5 g/100g) + Octisalate (5 g/100mL) + Octocrylene (2.5 g/100mL) + Oxybenzone (6 g/100mL) + Oxybenzone (6 g/100g) + Oxybenzone (6 g/100mL) + Zinc acetate dihydrate (1 g/100mL)		Topical	CoreTex Products	2019-11-27	Not applicable
Diclotrex	Synthetic camphor (4 g/100g) + Diclofenac sodium (16.05 mg/1mL) + Menthol (10 g/100g)	Kit	Topical	PureTek Corporation	2018-10-23	2028-10-19
Migranow	Synthetic camphor (4 g/100g) + Menthol (10 g/100g) + Sumatriptan succinate (50 mg/1)	Kit	Oral; Topical	PureTek Corporation	2016-04-18	Not applicable
Pain ReliefRoll On Roll On	Synthetic camphor (2.8 g/70g) + Menthol (7 g/70g) + Methyl salicylate (21 g/70g)	Liquid	Topical	Creations Garden Natural Products, Inc.	2010-03-10	Not applicable
Pain Relieving Ultra Strength	Synthetic camphor (2.28 g/57g) + Menthol (5.7 g/57g) + Methyl salicylate (9 g/57g)	Cream	Topical	Creation's Garden Natural Products, Inc	2010-03-31	Not applicable
Preferred Plus Medicated Lip Balm	Synthetic camphor (17 mg/1g) + Menthol (7 mg/1g) + Phenol (4 mg/1g)	Stick	Topical	Kinray	2007-02-28	Not applicable

Chemical Identifiers

UNII: 5TJD82A1ET
CAS number: 76-22-2
InChI Key: DSSYKIVIOFKYAU-UHFFFAOYSA-N
InChI: InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3
IUPAC Name: 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
SMILES: CC1(C)C2CCC1(C)C(=O)C2

References

General References

Not Available

External Links

KEGG Compound: C18369
ChemSpider: 2441
RxNav: 1371994
ChEBI: 36773
ChEMBL: CHEMBL15768

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Tape	Topical
Aerosol, spray	Cutaneous; Topical; Transdermal
Spray	Topical
Cream	Topical	5 mg/100g
Lotion	Topical
Ointment	Topical	10 g/100g
Gel	Topical	3 g/100mL
Gel	Topical	30 mg/1mL
Oil	Percutaneous; Topical; Transdermal
Kit	Topical
Paste	Topical
Ointment	Topical	1.24 g/100g
Liquid	Respiratory (inhalation)	155 mg/1mL
Gel	Topical
Ointment	Respiratory (inhalation)
Salve	Topical
Oil	Topical	0.03 kg/1kg
Cream	Topical	3 g/100g
Gel	Topical	4.5 mg/1g
Ointment	Topical	0.6 g/100g
Solution	Topical
Gel	Transdermal
Patch	Transdermal
Ointment	Topical
Lotion	Respiratory (inhalation)
Liquid	Respiratory (inhalation)	0.623 g/10mL
Ointment	Topical	11 g/100g
Liquid	Topical	110 mg/1mL
Shampoo	Topical	0.001 g/100mL
Liniment	Topical
Plaster	Topical; Transdermal
Patch	Cutaneous; Topical; Transdermal
Cream	Topical	50 mg/1mL
Suppository	Rectal	0.025 g/1g
Plaster	Topical
Oil	Topical
Kit	Oral; Topical
Plaster	Transdermal	3 g/100g
Cream	Topical	3.18 g/100g
Cream	Topical	3.2 g/100g
Cream	Topical	3.58 g/114g
Cream	Topical	31 mg/1g
Liquid	Topical
Jelly	Topical
Ointment	Topical	4 g/100g
Cloth	Topical	1 mL/1
Spray	Topical	1 mL/30mL
Liquid	Topical	0.0198 g/1g
Tincture	Topical
Patch	Topical
Stick	Topical
Cream	Cutaneous; Topical
Ointment	Cutaneous; Topical
Gel	Cutaneous; Topical
Plaster	Topical	3 1/1001
Patch	Percutaneous; Topical; Transdermal
Liquid	Respiratory (inhalation)	6.2 g/118mL
Solution	Cutaneous
Patch	Topical	0.13 g/100g
Gel	Percutaneous; Topical; Transdermal
Liquid	Respiratory (inhalation)	.623 g/10mL
Cream	Topical
Liquid	Cutaneous; Topical; Transdermal
Plaster	Transdermal
Inhalant	Respiratory (inhalation)	62 mg/1mL
Liquid	Respiratory (inhalation)	0.062 g/1mL
Oil	Transdermal
Solution	Nasal
Oil	Topical	4 g/100mL
Liniment	Percutaneous; Transdermal

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	0.88 mg/mL	ALOGPS
logP	2.85	ALOGPS
logP	2.55	ChemAxon
logS	-2.2	ALOGPS
pKa (Strongest Basic)	-7.5	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	1	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	17.07 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	44.49 m³·mol^-1	ChemAxon
Polarizability	17.74 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	1	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Spectrum	Spectrum Type	Splash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)	Predicted LC-MS/MS	Not Available

Drug created at June 29, 2018 14:55 / Updated at September 28, 2021 21:54

Synthetic camphor

Identification

Structure for Synthetic camphor (DB14156)

Pharmacology

Interactions

Products

Categories

Chemical Identifiers

References

Clinical Trials

Pharmacoeconomics

Properties

Spectra