Search
Piperaquine
go.drugbank.com/drugs/DB13941ApprovedInvestigationalIt has come back into use in combination with the artemisinin derivative [DB11638] as part of the combination product Eurartesim [FDA Label]. … Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550].
Poliovirus type 1 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10795ApprovedInvestigationalPoliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis … The vaccine contains purified and inactivated poliovirus type 1 that were grown from a continuous line of monkey kidney cells.
Mixtures: Dt Polio Adsorbed - Sus ImPoliovirus type 3 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10797ApprovedInvestigationalPoliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis … The vaccine contains purified and inactivated poliovirus type 3 that were grown from a continuous line of monkey kidney cells.
Mixtures: Dt Polio Adsorbed - Sus ImTaurocholic acid
go.drugbank.com/drugs/DB04348ApprovedIt acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
Categories: Compounds used in a research, industrial, or household settingBosutinib
go.drugbank.com/drugs/DB06616ApprovedInvestigationalPhiladelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein. … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexBos taurus hair
go.drugbank.com/drugs/DB10856ApprovedBos taurus hair is used in allergenic testing.
Mixtures: Animal Allergens, AP Cattle Hair and Dander, Animal Allergens, AP Cattle Hair and DanderAvutometinib
go.drugbank.com/drugs/DB15254ApprovedInvestigational[L53203] It has been under investigation in humans since at least 2012. … Avutometinib is a small molecule kinase inhibitor targeted against RAF/MEK1, key regulators of the RAS/RAF/MEK/ERK (MAPK) pathway.
Hydroxyprogesterone caproate
go.drugbank.com/drugs/DB06789ApprovedIt is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). … FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy
Alefacept
go.drugbank.com/drugs/DB00092ApprovedWithdrawnImmunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. Produced by CHO cells,...
Thrombin alfa
go.drugbank.com/drugs/DB11572ApprovedThrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically converted to a two-chain active form (using a protein derived from snakes) and is purified by a chromatographic … Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line.