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Azithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalAzithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine].
Categories: Experimental Unapproved Treatments for COVID-19, P-glycoprotein inhibitorsProducts: AZITHROMYCIN FOR INJECTION 500 MG/VIAL , 10 ML LYO VIAL, AZITIN 200 MG/5 ML ORAL SÜSPANSIYON IÇIN KURU TOZ, 15 MLEDIT-101
go.drugbank.com/drugs/DB18687InvestigationalEDIT-101 is a recombinant adeno-associated virus pseudotyped with serotype 5 viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein 9) gene editing
Synonyms: a recombinant adeno-associated virus pseudotyped with serotype 5 viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein 9) gene editing constructsAtenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … [A235850,A235855] A Cochrane review of patients being treated for primary hypertension shows that atenolol shows a risk ratio of 0.88 for cardiovascular disease risk and a risk ratio of 0.99 for mortality
Synonyms: 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol, 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamideMixtures: TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADET, TENORETIC 100 MG/25 MG FILM TABLET, 28 ADETMethimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigational[L8336,L8339] On a weight basis, methimazole is 10 times more potent than the other major antithyroid thionamide used in North America, [propylthiouracil],[L8339] and is the active metabolite of the … Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: 1-Methylimidazole-2(3H)-thioneApixaban
go.drugbank.com/drugs/DB06605ApprovedInvestigationalIt is marketed under the name Eliquis[Label,L6043]. Apixaban was approved by the FDA on December 28, 2012[L6043].
Mixtures: ELIQUIS 30-Day Starter Pack, ELIQUIS 30-Day Starter PackCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesUDP-alpha-D-glucuronic acid
go.drugbank.com/drugs/DB03041ExperimentalA nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. … It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Uridine-5'-diphosphate-glucuronic acid, UDP-D-glucuronateGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[A233565] Glycopyrronium was originally granted FDA approval on 11 August 1961.[L33090] … [L33110] It is one of the most commonly prescribed anticholinergic medications.
Mixtures: TRYDONİS 87 MCG/5 MCG/9 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 120 DOZ, TRİMBOW 87/5/9 MCG AEROSOL İNHALASYON ÇÖZELTİSİ, 120 DOZCategories: MATE 1 Substrates, Heterocyclic Compounds, 1-RingGavorestat
go.drugbank.com/drugs/DB16707InvestigationalGavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).
Synonyms: 2-(4-Oxo-3-((5-(Trifluoromethyl)Benzo[D]Thiazol-2-Yl)Methyl)-3,4-Dihydrothieno[3,4-D]Pyridazin-1-Yl)Acetic Acid, AT-007Orismilast
go.drugbank.com/drugs/DB19042InvestigationalOrismilast is under investigation in clinical trial NCT05190419 (Study to Assess the Efficacy and Safety of Orismilast in Psoriasis).
Synonyms: 2-(3,5-dichloro-1-oxido-4-pyridinyl)-1-(7-(difluoromethoxy)-2',3',5',6'-tetrahydro-1',1'-dioxidospiro(1,3-benzodioxole-2,4'-(4h)thiopyran)-4-yl)ethanoneMetacavir
go.drugbank.com/drugs/DB19084InvestigationalMetacavir is under investigation in clinical trial NCT02965859 (The Safety and Dose-range Study of Metacavir Enteric-coated Capsules in Patients With Chronic Hepatitis B).
Synonyms: ((2s,5r)-5-(2-amino-6-methoxy-purin-9-yl)tetrahydrofuran-2-yl)methanol, 2',3'-dideoxy-6-o-methylguanosineCategories: Heterocyclic Compounds, 2-Ring