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Displaying results 2391 - 2400 of 5451 in total
  1. Drug

    Foretinib

    go.drugbank.com/drugs/DB12307
    Investigational

    It inhibits the activation of MET, RON, ERK and AKT, decreased proliferation and increased apoptosis.

  2. Drug

    Rimegepant

    go.drugbank.com/drugs/DB12457
    ApprovedInvestigational

    [L11028] It received FDA approval on February 27, 2020 for the acute treatment migraine headache,[L11974] and was subsequently approved by the European Commission in April 2022 for both the treatment and

  3. Drug

    Nabilone

    go.drugbank.com/drugs/DB00486
    ApprovedInvestigational

    it is considered to be twice as active as Δ⁹-THC. … Though it was approved by the FDA in 1985, the drug only began marketing in the United States in 2006. It is also approved for use in treatment of anorexia and weight loss in patients with AIDS.

    Products: Canemes 1 mg Kapseln
  4. Drug

    Colletotrichum coccodes

    go.drugbank.com/drugs/DB10824
    Approved

    Colletotrichum coccodes is a fungus which can provoke allergic reactions. Colletotrichum coccodes extract is used in allergenic testing.

    Mixtures: Treatment Set TS128871
  5. Drug

    Desflurane

    go.drugbank.com/drugs/DB01189
    ApprovedInvestigational

    It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted FDA approval on 18 September 1992.[L30285]

  6. Drug

    Entrectinib

    go.drugbank.com/drugs/DB11986
    ApprovedInvestigational

    [L8081] It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors.

    Products: ROZLYTREK 200 MG SERT KAPSÜL, 90 ADET, ROZLYTREK 100 MG SERT KAPSÜL , 30 ADET
  7. Drug

    Olezarsen

    go.drugbank.com/drugs/DB18728
    ApprovedInvestigational

    [L52028] It is also being investigated for the treatment of hyperlipidemia.[A264898,A264903]

    Synonyms: DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-M5C-T-T-G-T-M5C-M5C-A-G-M5C-(2'-O-(2-METHOXYETHYL)
  8. Drug

    Pilocarpine

    go.drugbank.com/drugs/DB01085
    ApprovedInvestigational

    A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist. Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine ...

    Mixtures: E-pilo-2 Oph Soln, E-pilo-6 Oph SolnProducts: SALAGEN ® 7.5 MG, SALAGEN TABLET 5 mg
  9. Drug

    Ranirestat

    go.drugbank.com/drugs/DB05327
    Investigational

    Ranirestat is a structurally novel and stereospecifically potent aldose reductase (AKR1B; EC 1.1.1.21) inhibitor, which contains a succinimide ring that undergoes ring-opening at physiological pH levels … It has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy.

  10. Drug

    Sinecatechins

    go.drugbank.com/drugs/DB01266
    ApprovedInvestigationalNutraceutical

    Catechins constitute 85 to 95% (by weight) of the total drug substance which includes more than 55% of Epigallocatechin gallate (EGCg), other catechin derivatives such as Epicatechin (EC), Epigallocatechin … It is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis, and is a mixture of catechins and other green tea components.

    Synonyms: Polyphenon E