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Displaying results 2401 - 2410 of 8009 in total

Drug
Rimegepant
go.drugbank.com/drugs/DB12457
ApprovedInvestigational
[L11028] It received FDA approval on February 27, 2020 for the acute treatment migraine headache,[L11974] and was subsequently approved by the European Commission in April 2022 for both the treatment and … safer for use in patients with contraindications to standard therapy.
Drug
Obiltoxaximab
go.drugbank.com/drugs/DB05336
Approved
Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin.
Categories: Antiinfectives for Systemic Use
Drug
Isoetharine
go.drugbank.com/drugs/DB00221
Approved
Isoetharine is a fast-acting bronchodilator used for emphysema, bronchitis and asthma.[A330]
Categories: Adrenergics for Systemic Use, Drugs for Obstructive Airway Diseases
Drug
Telavancin
go.drugbank.com/drugs/DB06402
ApprovedInvestigational
Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. MRSA is an important pathogen capable of causing hospita...
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
Drug
Nizatidine
go.drugbank.com/drugs/DB00585
Approved
The drug is used for the treatment of duodenal ulcers.
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)
Drug
Oteseconazole
go.drugbank.com/drugs/DB13055
ApprovedInvestigational
[L41635] Unlike previous-generation azole antifungals, oteseconazole has a high selectivity for CYP51 and little interaction with human cytochrome P450s. … [L41635] This drug was approved by the FDA on April 26, 2022.[L41645]
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic Use
Drug
Azelastine
go.drugbank.com/drugs/DB00972
ApprovedInvestigational
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic … [L8240,L8270] Azelastine is also available in combination with fluticasone propionate as a nasal spray marketed under the trade name Dymista™, which is indicated for the symptomatic treatment of seasonal
Categories: Antihistamines for Systemic Use
Drug
Lumacaftor
go.drugbank.com/drugs/DB09280
ApprovedInvestigational
[A20343] Improvements in lung function (ppFEV1) were found to be statistically significant, but minimal, with only a 2.6-3.0% change from baseline with more than 70% of patients failing to achieve an absolute … Approved for use by the Food and Drug Administration in July 2015 and by Health Canada in January 2016, Orkambi was the first combination product approved for the management of Cystic Fibrosis with delta-F508
Drug
Bilastine
go.drugbank.com/drugs/DB11591
Approved
Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Categories: Antihistamines for Systemic Use
Drug
Uprifosbuvir
go.drugbank.com/drugs/DB15206
Investigational
Uprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis … C Genotype (GT)1 and GT2 Infection (MK-3682-011)).