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Influenza A virus A/Kansas/14/2017 X-327 (H3N2) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15516ApprovedInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Synonyms: Influenza A virus A/Kansas/14/2017 X-327 (H3N2) antigen (formaldehyde inactivated)Mixtures: FLUARIX TETRA SUSPENSION FOR INJECTIONBrodalumab
go.drugbank.com/drugs/DB11776ApprovedInvestigationalBrodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque psoriasis. … Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis.
Categories: Interleukin-17 Receptor A Antagonist, Interleukin 17 Receptor A AntagonistsLymecycline
go.drugbank.com/drugs/DB00256ApprovedInvestigationalWithdrawnLymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections. … [L13880,L13883] It has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and efficacy.[A203255] Lymecycline was initially discovered in 1961.
Synonyms: Tetracycline-L-methylenelysine, Tetracycline-L-methylene lysineCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseOleic Acid
go.drugbank.com/drugs/DB04224ApprovedInvestigationalVet approvedAn unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. … (Stedman, 26th ed)
Mixtures: Huile D'onagre Vitamin E, Gla 130 Primrose OilBenznidazole
go.drugbank.com/drugs/DB11989ApprovedInvestigational[L939] It is the first treatment made available in the United States for Chagas disease. … Benznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
HIV-1 retropepsin
go.drugbank.com/bio_entities/BE0003339TargetHuman immunodeficiency virus 1Synonyms: Pol proteinDiethylcarbamazine
go.drugbank.com/drugs/DB00711ApprovedInvestigationalVet approvedWithdrawnAn anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Degarelix
go.drugbank.com/drugs/DB06699ApprovedInvestigationalDegarelix is used for the treatment of advanced prostate cancer. … Chemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which are D-amino acids. FDA approved on December 24, 2008.
Products: Firmagon 120mg Powder and Solvent for Solution for Injection, Firmagon 80mg Powder and Solvent for Solution for InjectionPonatinib
go.drugbank.com/drugs/DB08901ApprovedInvestigationalPonatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSeladelpar
go.drugbank.com/drugs/DB12390ApprovedInvestigational[L51149] On August 14, 2024, seladelpar was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis,[L51154] which is a condition associated with aberrant bile acid metabolism … Seladelpar is a peroxisome proliferator-activated receptor (PPAR)-delta (δ) agonist. Seladelpar is a single enantiomer of the R-configuration.