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Displaying results 2411 - 2420 of 10000 in total
  1. Drug

    Vericiguat

    go.drugbank.com/drugs/DB15456
    ApprovedInvestigational

    [A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis and thereby helps to prevent the myocardial and vascular dysfunction associated with decreased sGC … [A227458,A227488] Cyclic GMP acts as a second messenger, activating a number of downstream signaling cascades that elicit a broad variety of effects, and these diverse cellular effects have implicated

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesProducts: VERQUVO 5 MG FİLM KAPLI TABLET , 14 ADET, VERQUVO 10 MG FİLM KAPLI TABLET , 14 ADET
  2. Drug

    Isosorbide dinitrate

    go.drugbank.com/drugs/DB00883
    ApprovedInvestigational

    A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.

    Mixtures: Isosorbide dinitrate and hydralazine hydrochloride, Isosorbide Dinitrate and Hydralazine HydrochlorideCategories: Nitrates and Nitrites, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  3. Drug

    TK-112690

    go.drugbank.com/drugs/DB18822
    Investigational

    Synonyms: O2,2'-anhydro-5-methyluridine, 6h-furo(2',3':4,5)oxazolo(3,2-a)pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-7-methyl-, (2r,3r,3as,9ar)-
  4. Drug

    (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide

    go.drugbank.com/drugs/DB07397
    Experimental

    Synonyms: (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide
  5. Drug

    Nicotine

    go.drugbank.com/drugs/DB00184
    ApprovedInvestigational

    It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.

    Synonyms: (S)-3-(1-methylpyrrolidin-2-yl)pyridine, (S)-3-(N-methylpyrrolidin-2-yl)pyridineMixtures: Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening
  6. Drug

    Atosiban

    go.drugbank.com/drugs/DB09059
    ApprovedInvestigational

    Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form. … Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used intravenously to halt premature labor.

    Categories: Amino Acids, Peptides, and Proteins, Genito Urinary System and Sex HormonesProducts: Atosiban EVER Pharma 75 mg/10 ml Konzentrat zur Herstellung einer Infusionslösung, TRACTOCILE 7,5 MG/ML ENJEKSIYONLUK ÇÖZELTİ, 0,9 ML FLAKON, 1 ADET
  7. Drug

    Tulmimetostat

    go.drugbank.com/drugs/DB19446
    Investigational

    Tulmimetostat is under investigation in clinical trial NCT05467748 (EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer).

    Synonyms: (2R)-7-chloro-2-[trans-4-(3-methoxyazetidin-1-yl)cyclohexyl]-2,4-dimethyl-N-{[6-methyl-4-(methylsulfanyl)-2-oxo-1,2-dihydropyridin-3-yl]methyl}-2H-1,3-benzodioxole-5-carboxamide, 1,3-Benzodioxole-5-carboxamide, 7-chloro-N-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-[trans-4-(3-methoxy-1-azetidinyl)cyclohexyl]-2,4-dimethyl-, (2R)-
  8. Drug

    Cefadroxil

    go.drugbank.com/drugs/DB01140
    ApprovedInvestigationalVet approvedWithdrawn

    Long-acting, broad-spectrum, water-soluble, cephalexin derivative.

    Synonyms: D-CefadroxilCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    A metallic element of atomic number 30 and atomic weight 65.38. … It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division.

    Mixtures: FENYSOL-Z 40 MG + 15 MG/5 ML ŞURUP, 100 ML, ZİNOMAG 30 MG /300 MG FİLM KAPLI TABLET, 40 ADETCategories: Diet, Food, and Nutrition, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  10. Drug

    Methadone

    go.drugbank.com/drugs/DB00333
    ApprovedInvestigational

    Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. … contraction of HIV and Hepatitis C and other complications including skin infections, abscesses, or endocarditis.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 6-Dimethylamino-4,4-diphenyl-3-heptanone