Search

Displaying results 2411 - 2420 of 10000 in total
  1. Drug

    Icodextrin

    go.drugbank.com/drugs/DB00702
    ApprovedInvestigational

    It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways. … Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers.

    Mixtures: SOLUCIÓN DP PISA DXT, EXTRANEAL CON ICODEXTRIN AL 7.5%Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Dextropropoxyphene

    go.drugbank.com/drugs/DB00647
    ApprovedIllicitWithdrawn

    Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States. … The levo-isomer appears to exhibit a very limited antitussive effect.

    Synonyms: d-PropoxypheneMixtures: Darvocet-N 100, Darvocet-N 50
  3. Drug

    Iophendylate

    go.drugbank.com/drugs/DB01187
    Approved

    Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). … In 1942 Van Wagenen (a neurosurgical colleague of Warrens, at the University of Rochester) identified Iophendylate as causing chemical meningitis in 30 patients where "space-displacing masses within the

    Synonyms: Ethyl 10-(p-iodophenyl)-undecanoate, Ethyl 10-(p-iodophenyl)undecylateCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Talquetamab

    go.drugbank.com/drugs/DB16678
    ApprovedInvestigational

    Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. … [L47765] Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and CD3 on T cells.

    Synonyms: ANTIBODY; BISPECIFIC GAMMA4 HEAVY CHAIN HUMANIZED AN, IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL
  5. Drug

    SNS-314

    go.drugbank.com/drugs/DB06134
    Investigational

    SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. … SNS-314 inhibits tumor growth in a variety of preclinical models, and it is now being tested in single agent Phase 1 studies in patients with advanced solid tumours.

    Salts: SNS-314 mesylateSynonyms: 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea
  6. Drug

    Betamethasone phosphate

    go.drugbank.com/drugs/DB14669
    ApprovedVet approved

    Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone] to agonize glucocorticoid receptors.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Substrates
  7. Target

    Tumor necrosis factor ligand superfamily member 15

    go.drugbank.com/bio_entities/BE0010966
    TargetHumans

    Cytokine that signals through TNFRSF25 receptor (PubMed:11911831). Functions as a T-cell costimulator, that increases IL-2 responsiveness and secretion of proinflammatory cytokines which enhances T-cell activation, proliferation and the ...

    Polypeptides: Tumor necrosis factor ligand superfamily member 15
  8. Drug

    Molnupiravir

    go.drugbank.com/drugs/DB15661
    Investigational

    [A193029] Recent studies have shown molnupiravir inhibits replication of human and bat coronaviruses, including SARS-CoV-2, in mice and human airway epithelial cells. … Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of [N4-hydroxycytidine].

  9. Drug

    Clofedanol

    go.drugbank.com/drugs/DB04837
    ApprovedWithdrawn

    Clofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.

    Mixtures: Vanacof G, DryMax AF
  10. Drug

    Pumactant

    go.drugbank.com/drugs/DB04955
    Experimental

    It is a unique formulation of the naturally occurring phospholipids Dipalmitoylphosphatidycholine (DPPC) and Phosphatidyl Glycerol (PG). … Pumactant is a synthetic surfactant used for treating respiratory distress syndrome in neonates.