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Displaying results 2421 - 2430 of 3178 in total
  1. Drug

    Pegcetacoplan

    go.drugbank.com/drugs/DB16694
    ApprovedInvestigational

    Pegcetacoplan is a complement inhibitor indicated in the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Prior to its FDA approval, patients with PNH were typically treated with the C5 inhibiting monoclonal antibody eculizumab. P...

  2. Drug

    Tisotumab vedotin

    go.drugbank.com/drugs/DB16732
    ApprovedInvestigational

    Tisotumab vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human IgG1-kappa antibody conjugated to monomethyl auristatin E (MMAE), a microtubule-disrupting agent, via a protease-cl...

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  3. Drug

    CP-96345

    go.drugbank.com/drugs/DB16744
    Experimental

    Categories: Substance P, antagonists & inhibitors
  4. Drug

    Cinchonidine

    go.drugbank.com/drugs/DB16831
    Experimental

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  5. Drug

    Remibrutinib

    go.drugbank.com/drugs/DB16852
    ApprovedInvestigational

    Remibrutinib is a selective Bruton's tyrosine kinase inhibitor. The FDA approved remibrutinib on September 30, 2025 as the only oral, targeted treatment for chronic spontaneous urticaria. Bruton's tyrosine kinase plays a role in B cell r...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  6. Drug

    Tyrosol

    go.drugbank.com/drugs/DB16855
    Experimental

    Synonyms: p-TyrosolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates
  7. Drug

    Linzagolix

    go.drugbank.com/drugs/DB17083
    ApprovedInvestigational

    Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis. It is similar to ...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitors
  8. Drug

    Norclobazam

    go.drugbank.com/drugs/DB17092
    Investigational

    Synonyms: N-desmethylclobazamCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Substrates
  9. Drug

    XomaZyme-791

    go.drugbank.com/drugs/DB17216
    Experimental

    Categories: N-Glycosyl Hydrolases
  10. Drug

    Redaporfin

    go.drugbank.com/drugs/DB17219
    Investigational

    Synonyms: 3,3',3'',3'''-(7,8,17,18-tetrahydroporphyrin-5,10,15,20-tetrayl)tetrakis(2,4-difluoro-n-methylbenzenesulfonamide), Benzenesulfonamide, 3,3',3'',3'''-(7,8,17,18-tetrahydro-21h,23h-porphine-5,10,15,20-tetrayl)tetrakis(2,4-difluoro-n-methyl-Categories: P-glycoprotein substrates