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Ethiodized oil
go.drugbank.com/drugs/DB00965ApprovedInvestigationalEthiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil.
Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedProducts: LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ , 5 ML, LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 10 MLZiprasidone
go.drugbank.com/drugs/DB00246ApprovedInvestigational[A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower incidence of metabolic adverse effects compared to other medications in the same class.[A190525] … [A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to treat manic episodes in bipolar disorder although the mechanism of action is unknown.
Categories: Adrenergic alpha-1 Receptor Antagonists, Heterocyclic Compounds, 1-RingProducts: ZELDOX 20 MG KAPSUL, 56 ADET, Zeldox 10 mg/ml Suspension zum EinnehmenAmbrisentan
go.drugbank.com/drugs/DB06403ApprovedInvestigationalIt is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. … Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesSynonyms: (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acidZonisamide
go.drugbank.com/drugs/DB00909ApprovedInvestigational[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors … In 1989, it was approved for commercial use in Japan. The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383]
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsSynonyms: Benzo[d]isoxazol-3-yl-methanesulfonamide, 1,2-Benzisoxazole-3-methanesulfonamideDeudomperidone
go.drugbank.com/drugs/DB19055InvestigationalDeudomperidone is under investigation in clinical trial NCT05832151 (A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis).
Synonyms: 2h-benzimidazol-2-one-4,5,6,7-d4, 1-(3-(4-(5-chloro-2,3-dihydro-2-oxo-1h-benzimidazol-1-yl)-1-piperidinyl)propyl)-1,3-dihydro-, 3-(3-(4-(5-chloro-2-oxo-3hbenzimidazol-1-yl)-1- piperidyl)propyl)-4,5,6,7- tetradeutero-1h-benzimidazol-2- oneAzelaic acid
go.drugbank.com/drugs/DB00548ApprovedInvestigationalAzelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. … It is also produced by _Malassezia furfur_, also known as _Pityrosporum ovale_, which is a species of fungus that is normally found on human skin.
Mixtures: Azelaic Acid 15% / Niacinamide 4%, 2% Salicylic Acid FACIAL CLEANSERSynonyms: n-nonanedioic acidTofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. … It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: Tositin 10 mg Film Kaplı Tablet, 56 ADET, XELJANZ XR 11 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADETPalonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalIt is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of … As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.
Categories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT3 Receptor AntagonistsSynonyms: 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one, (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-oneIlacirnon
go.drugbank.com/drugs/DB16066InvestigationalIlacirnon (CCX-140) is under investigation in clinical trial NCT01440257 (A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria).
Synonyms: 4-Chloro-N-[5-methyl-2-(7H-pyrrolo[2,3-d]pyrimidin-4-ylcarbonyl)-3-pyridinyl]-3-(trifluoromethyl)benzenesulfonamideTuberculin purified protein derivative
go.drugbank.com/drugs/DB11601ApprovedThe purified protein fraction is isolated from culture media filtrates of a human strain of Mycobacterium tuberculosis. It is included in the World Health Organization's List of Essential Medicines. … Tuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis.
Categories: Compounds used in a research, industrial, or household settingProducts: PPD TÜBERKÜLIN 5 TU/ 0.1 ML INTRADERMAL ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 20 ADET, PPD TÜBERKÜLİN 100 TU/2 ML İNTRADERMAL ENJEKSİYONLUK ÇÖZELTİ, 20 ADET