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Ocifisertib
go.drugbank.com/drugs/DB18746InvestigationalSynonyms: (1R,2S)-2-[3-[(1E)-2-[4-[[(2R,6S)-2,6-Dimethyl-4-morpholinyl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5′-methoxyspiro[cyclopropane-1,3′-[3H]indol]-2′(1′H)-one, Spiro(cyclopropane-1,3'-(3h)indol)-2'(1'h)-one, 2-(3-((1e)-2-(4-(((2r,6s)-2,6-dimethyl-4-morpholinyl)methyl)phenyl)ethenyl)-1h-indazol-6-yl)-5'-methoxy-, (1r,2s)-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalmake it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no potential to produce, or be subject to, pharmacokinetic interactions[L8606,L8600,L8615] - these characteristics
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesProducts: LEV-END 500 MG/5 ML KONSANTRE İNFÜZYON ÇÖZELTİSİ İÇEREN FLAKON, 10 ADET, EPILECURE 500 MG/5 ML KONSANTRE INFÜZYON ÇÖZELTISI,10 ADETMethylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalThe intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. … Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered the market.
Mixtures: Me NaPhos MB Hyo 1, BUCO-BLEU KOLLUTUVAR, 15 MLCategories: MATE 1 Inhibitors, MATE 2 InhibitorsObecabtagene autoleucel
go.drugbank.com/drugs/DB17362ApprovedInvestigational[L52450] Obecabtagene autoleucel was also investigated in other hematological cancers and systemic lupus erythematosus.[A265045] … [A265040,A265045] It works by targeting B-cell-specific CD19 surface markers present on malignant B cells.
Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsSynonyms: SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION., AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) OBTAINED BY APHERESIS TRANSDUCED EX VIVO WITH A NON-REPLICATING, SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODINGBuspirone
go.drugbank.com/drugs/DB00490ApprovedInvestigationalBelonging to the azaspirodecanedione drug class,[A180991] buspirone is a serotonin 5-HT<sub>1A</sub> receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates … Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile.
Categories: Heterocyclic Compounds, 1-Ring, Miscellaneous Anxiolytics Sedatives and HypnoticsSynonyms: 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dioneFerric carboxymaltose
go.drugbank.com/drugs/DB08917ApprovedInvestigationalFerric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Categories: Compounds used in a research, industrial, or household settingProducts: Ferapplic 500 mg/10 ml Enjeksiyonluk/İnfüzyonluk Çözelti, 5 flakon, Ferapplic 500 mg/10 ml Enjeksiyonluk/İnfüzyonluk Çözelti, 1 flakonTrimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalTrimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. … Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries.
Synonyms: 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoatSalts: Trimebutine 3-thiocarbamoylbenzenesulfonateAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalAzithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine].
Categories: Experimental Unapproved Treatments for COVID-19, cefixime and azithromycinProducts: AZITHROMYCIN FOR INJECTION 500 MG/VIAL , 10 ML LYO VIAL, AZITIN 200 MG/5 ML ORAL SÜSPANSIYON IÇIN KURU TOZ, 15 MLVinblastine
go.drugbank.com/drugs/DB00570ApprovedInvestigationalAntitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Categories: Antineoplastic and Immunomodulating Agents, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: VINCABLAS® 10 MG/VIAL, VINBLASTINE RICHTER 5 MG FLAKONCefditoren
go.drugbank.com/drugs/DB01066ApprovedCefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Categories: Heterocyclic Compounds, 2-RingProducts: CEFITEN 50 MG SASE, 21 ADET, CEFITEN 50 MG SASE, 42 ADET