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Displaying results 2431 - 2440 of 10000 in total
  1. Drug

    Influenza A virus A/Hong Kong/2671/2019 (H3N2) live (attenuated) antigen

    go.drugbank.com/drugs/DB15757
    Approved

    Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.

    Synonyms: Influenza A virus A/Hong Kong/2671/2019 (H3N2) live (attenuated) antigen
  2. Drug

    Asparaginase Erwinia chrysanthemi

    go.drugbank.com/drugs/DB08886
    ApprovedInvestigational

    [L1448] L-asparaginase was first identified in 1963,[A236344] and there are different formulations of L-asparaginase, including [Asparaginase Escherichia coli] and a pegylated form of this enzyme, [Pegaspargase … [A236344] Studies show that substitution of _Erwinia_ asparaginase for _E. coli_-derived asparaginase following an allergic reaction has been safe and effective.

    Synonyms: Erwinia L-asparaginase, L-asparaginase (Erwinia)
  3. Drug

    XEN-D0101

    go.drugbank.com/drugs/DB06020
    Experimental

    XEN-D0101 works by being a selective antagonist of the voltage-gated potassium channel Kv1.5.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Target

    Translocator protein

    go.drugbank.com/bio_entities/BE0000736
    TargetHumans

    Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678)

    Synonyms: Mitochondrial benzodiazepine receptor, Peripheral-type benzodiazepine receptor
  5. Drug

    Imagabalin

    go.drugbank.com/drugs/DB12105
    Investigational

    Imagabalin has been investigated in Generalized Anxiety Disorder.

  6. Drug

    Sulfamethylthiazole

    go.drugbank.com/drugs/DB15882
    Experimental

    Sulfamethylthiazole is a sulfonamide antibacterial agent.[A275183]

    Synonyms: 4-Amino-N-(4-methyl-2-thiazolyl)benzenesulfonamide, N(sup 1)-(4-Methyl-2-thiazolyl)sulfanilamideInternational brands: Toriseptin M
  7. Drug

    Isavuconazole

    go.drugbank.com/drugs/DB11633
    ApprovedInvestigational

    Resistance to isavuconazole has been associated with the mutation in the target gene CYP51 [FDA Label]. … It is proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a repeat loading dose when transitioning from an IV to an oral formulation [A32026].

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2B6 Inducers
  8. Drug

    LErafAON

    go.drugbank.com/drugs/DB04973
    Investigational

    Phase I/II trials commenced in March 2001 and were ongoing as of June 2003. … NeoPharm is developing liposome-encapsulated, c-Raf antisense oligodeoxynucleotides (LErafAON) for the potential treatment of various solid tumors, including those that have become resistant to radiation

  9. Drug

    1-Testosterone

    go.drugbank.com/drugs/DB01481
    IllicitInvestigational

    1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring.

    Synonyms: 1-T, 17beta-hydroxy-5alpha-androst-1-en-3-one
  10. Drug

    Dolcanatide

    go.drugbank.com/drugs/DB13112
    Investigational

    Dolcanatide has been investigated in Exposure.

    Categories: Guanylyl Cyclase C Agonists