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Copper-transporting ATPase 2
go.drugbank.com/bio_entities/BE0003664TransporterHumansCopper ion transmembrane transporter involved in the export of copper out of the cells. … It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload
Polypeptides: Copper-transporting ATPase 2Synonyms: Copper pump 2CMV DNA Terminase Complex
go.drugbank.com/bio_entities/BE0010221TargetHuman CytomegalovirusForms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. … Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.
Sipuleucel-T
go.drugbank.com/drugs/DB06688ApprovedInvestigationalFood and Drug Administration (FDA) on April 29, 2010, to treat asymptomatic or minimally symptomatic metastatic Hormone-Refractory Prostate Cancer (HRPC). … The treatment initially cost $93,000 at the time of FDA approval, but rose to over $100,000 in 2014.
Categories: Complex MixturesPertussis vaccine
go.drugbank.com/drugs/DB15274ApprovedInvestigationalPertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy).
Mixtures: SII DIPHTHERIA,TETANUS &PERTUSSIS VACCINE ADSORBED-20 DOSES, Boostrix Injektionssuspension in einer FertigspritzeCategories: Complex MixturesTegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawn[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause dangerous cardiovascular … Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).
Molybdenum
go.drugbank.com/drugs/DB11137ApprovedInvestigationalMolybdenum is a chemical element with symbol Mo and atomic number 42. As it is not a naturally occuring free metal on Earth, molybdenum is found only in various oxidation states in minerals. … Molybdenum is commonly used in metallurgy and other chemical applications however it has essential biological roles in organisms and microorganisms.
Mixtures: Ribotin-E, Multitol-MImmunoglobulin kappa variable 3-20
go.drugbank.com/bio_entities/BE0000616TargetHumansV region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Polypeptides: Immunoglobulin kappa variable 3-20Synonyms: Ig kappa chain V-III region SIELasofoxifene
go.drugbank.com/drugs/DB06202ApprovedInvestigationalWithdrawnIt gained approval by European Commission in March 2009. … Later Fablyn was developed as a result of a research collaboration between Pfizer and Ligand Pharmaceuticals with a newly submitted New Drug Application in 2008.
NADH
go.drugbank.com/drugs/DB00157ApprovedNutraceuticalIt is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). … It forms NADP with the addition of a phosphate group to the 2' position of the adenosyl nucleotide through an ester linkage. (Dorland, 27th ed)
Mixtures: Enl, HEPATAMINE %8 500 ML(SETLI)Betaine
go.drugbank.com/drugs/DB06756ApprovedInvestigationalNutraceutical[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and urine. … Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine.
Mixtures: Enl, Rocky Mountain Multiple Vit and Min Mega TabSynonyms: TMG, 2-N,N,N-trimethylammonio acetate