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Methacholine
go.drugbank.com/drugs/DB06709Approvedpulmonary function and causing symptoms such as difficulty breathing. … Asthma is a complex condition associated with phenomena such as airway hyperresponsiveness (AHR), in which the smooth muscle in the airways (ASM) excessively contracts in response to stimuli, reducing
Ferric derisomaltose
go.drugbank.com/drugs/DB15617ApprovedInvestigational[A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. This drug is a complex of iron (III) hydroxide and derisomaltose. … The latter is an iron carbohydrate oligosaccharide that works to release iron. Ferric derisomaltose was developed by Pharmacosmos Therapeutics ad was granted FDA approval in January 2020.
Hydroxyamphetamine
go.drugbank.com/drugs/DB09352ApprovedHydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes. … The main use of hydroxyamphetamines as eye drops is the diagnosis of Horner's syndrome which is characterized by nerve lesions.
Synonyms: p-hydroxyamphetamine, dl-p-hydroxyamphetamineAnemarrhena asphodeloides root
go.drugbank.com/drugs/DB14590InvestigationalMixtures: YOUNGCELLOGY AIOS LV SerumChamaecyparis obtusa leaf
go.drugbank.com/drugs/DB14686InvestigationalMixtures: Rhodd Ato Repair Body So ApTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalTranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. … It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent.
Products: TRANSAMINE 50 MG/ML IV ENJ COZELTI, 5 ML, TRANEXEL 250MG/5ML IV ENJEKSİYONLUK ÇÖZELTİRucaparib
go.drugbank.com/drugs/DB12332ApprovedInvestigationalRucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. PARP is an enzyme that plays an essential role in DNA repair. … an androgen receptor–directed therapy, confirming clinical benefit for an indication that previously had accelerated approval.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexLatanoprostene bunod
go.drugbank.com/drugs/DB11660ApprovedIn comparison, both latanoprost and latanoprostene bunod contain a latanoprost acid backbone. … Conversely however, latanoprostene bunod integrates an NO-donating moiety in lieu of the isopropyl ester typically found in latanoprost.
Icaridin
go.drugbank.com/drugs/DB14074InvestigationalIcaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine and a member of the piperidine chemical family. … Icaridin has been commonly used as a topically-applied insect repellent in various countries but was officially licensed for use in the United States in 2001 and Canada in 2012 [L4595].
Categories: Compounds used in a research, industrial, or household settingGuanabenz
go.drugbank.com/drugs/DB00629ApprovedWithdrawnGuanabenz is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates