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Displaying results 2461 - 2470 of 3889 in total
  1. Drug

    CLZ-2002

    go.drugbank.com/drugs/DB18638
    Investigational

    CLZ-2002 consists of allogeneic mesenchymal stem cells derived neuronal regeneration-promoting cells.

    Synonyms: allogeneic mesenchymal stem cells derived neuronal regeneration promoting cells
  2. Target

    Capsid protein

    go.drugbank.com/bio_entities/BE0010951
    TargetHepatitis B virus genotype A2 subtype adw2 (strain Rutter 1979)

    Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin

    Synonyms: Core antigen, Core protein
  3. Drug

    MDR-101

    go.drugbank.com/drugs/DB18513
    Investigational

    MDR-101 is a CD34+ hematopoietic stem and progenitor cells with CD3+ T-cells

  4. Drug

    Secukinumab

    go.drugbank.com/drugs/DB09029
    ApprovedInvestigational

    Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions ...

  5. Drug

    Cisapride

    go.drugbank.com/drugs/DB00604
    ApprovedWithdrawn

    In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. The FDA issued a warning letter regardi...

    Categories: para-Aminobenzoates
  6. Drug

    Momelotinib

    go.drugbank.com/drugs/DB11763
    ApprovedInvestigational

    [L48186] Myelofibrosis (MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative hematopoietic stem cells, leading to the release of cytokines and growth factors.

  7. Drug

    Ceftolozane

    go.drugbank.com/drugs/DB09050
    ApprovedInvestigational

    Ceftolozane is a semi-synthetic broad-spectrum fifth generation cephalosporin.

  8. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

    go.drugbank.com/bio_entities/BE0000473
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-13kD-B, Complex I subunit B13
  9. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

    go.drugbank.com/bio_entities/BE0000500
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-AQDQ, Complex I-18 kDa
  10. Drug

    Cetilistat

    go.drugbank.com/drugs/DB06586
    Investigational

    Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.