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Erenumab
go.drugbank.com/drugs/DB14039ApprovedInvestigationalErenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines … CGRP receptor, which is believed to play a critical role in migraine [L2823].
Products: PASURTA® 70MG/ML, PASURTA® 140 MG /MLEptinezumab
go.drugbank.com/drugs/DB14040ApprovedInvestigationalEptinezumab is a fully-humanized IgG1 antibody manufactured using yeast (_Pichia pastoris_) and developed by Lundbeck Seattle Biopharmaceuticals.
Products: Vyepti® 100 mg/mL concentrate for solution for infusionFremanezumab
go.drugbank.com/drugs/DB14041ApprovedInvestigationalFremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. … [L11779] Along with other recently approved anti-CGRP therapies such as [galcanezumab], [erenumab], and the oral CGRP antagonist [ubrogepant], fremanezumab represents an important step forward in the treatment
Products: AJOVY 225 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 3 ADET, AJOVY 225 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETGalcanezumab
go.drugbank.com/drugs/DB14042ApprovedInvestigationalGalcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). … [L42060] It is unknown if galcanezumab has an effect on pregnancy outcomes. A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women.[L42060]
Products: EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET, EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADETPalmidrol
go.drugbank.com/drugs/DB14043InvestigationalNutraceuticalPalmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets). … A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection.
Synonyms: N-(2-Hydroxyethyl)palmitamide, N-palmitoylethanolamineDichlorobenzene
go.drugbank.com/drugs/DB14046ApprovedWithdrawnIt is a constituent of the ear-wax removal product Cerumol. … Dichlorobenzene refers to any of, or a mixture of, three isomers consisting of benzene in which two of the hydrogen atoms are replaced by chlorine atoms: ortho-, meta-, and paradichlorobenzene.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesCannabidivarin
go.drugbank.com/drugs/DB14050InvestigationalCannabidivarin, also known as cannabidivarol or CBDV, is a non-psychoactive cannabinoid found within [DB14009]. … , which is a member of a large family of ion channels that are involved in the onset and progression of several types of epilepsy.
Synonyms: 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol, CBD-VMalacidin B
go.drugbank.com/drugs/DB14052ExperimentalMalacidin B, along with [DB14051], is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria [A33312]. … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin B appears to act via its own distinct mechanism.
Synonyms: Malacidin BSC-236
go.drugbank.com/drugs/DB14059ExperimentalSC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) [L2964] that has been studied in cancer therapy [A33375], lower back pain [A33376], and inflammation [A33373], [A33374
Categories: Heterocyclic Compounds, 1-RingDexverapamil
go.drugbank.com/drugs/DB14063ExperimentalSynonyms: (R)-verapamil, (+)-(R)-verapamilCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates