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Ilepcimide
go.drugbank.com/drugs/DB16942ExperimentalSynonyms: Piperidine, 1-(3-(1,3-benzodioxol-5-yl)-1-oxo-2-propenyl)-, (e)-, 1-((e)-3,4-(methylenedioxy)cinnamoyl)piperidineCategories: Heterocyclic Compounds, 1-RingAlogabat
go.drugbank.com/drugs/DB18708InvestigationalSynonyms: 3-pyridazinecarboxamide, 6-((5-methyl-3-(6-methyl-3-pyridinyl)-4-isoxazolyl)methoxy)-n-(tetrahydro-2h-pyran-4-yl)-Ebastine
go.drugbank.com/drugs/DB11742ApprovedInvestigationalWithdrawnEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: PINAVALT® 10 MG TABLETASRECUBIERTAS, EBAFIT 20 MG FILM KAPLI TABLET, 10 ADETDiphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalHowever, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. … As a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties.
Synonyms: 2-(benzhydryloxy)-N,N-dimethylethylamine, 2-diphenylmethoxy-N,N-demthylethanamineInternational brands: Dormarex 2Prednisolone phosphate
go.drugbank.com/drugs/DB14631ApprovedInvestigationalVet approved[A187463] Prednisolone phosphate was granted FDA Approval on 19 December 1973.[L14144] … Prednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
Mixtures: OFTALETYC® NFCategories: P-glycoprotein inducers, Cytochrome P-450 CYP2A6 InducersChloroquine
go.drugbank.com/drugs/DB00608ApprovedInvestigationalVet approved[A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment of COVID-19 was revoked on 15 June 2020. … [A191655] It was the drug of choice to treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and [mefloquine].
Categories: Heterocyclic Compounds, 2-Ring, Experimental Unapproved Treatments for COVID-19Synonyms: N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamineTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigationalCTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells. … Tremelimumab, formerly known as ticilimumab, is a fully human IgG2 monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4).
Categories: CTLA-4-directed Blocking AntibodyProducts: Imjudo Concentrate for Solution for Intravenous Infusion 20 mg/mL, Imjudo 25 mg/1.25 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adetLorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigationalLorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. … [A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977.
Synonyms: o-Chloroxazepam, o-ChlorooxazepamProducts: ATIVAN EXPIDET 1 MG TABLET, 20 ADET, ATIVAN EXPIDET 2.5 MG TABLET, 20 ADETLinagliptin
go.drugbank.com/drugs/DB08882ApprovedInvestigationalLinagliptin was approved by the FDA on May 2, 2011[L9557]. … Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050
Mixtures: GLYXAMBI® 10 MG/ 5 MG, GLYXAMBI® 10 MG/ 5 MGCategories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsChloroprocaine
go.drugbank.com/drugs/DB01161ApprovedInvestigationalSimilar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without methylparaben as a preservative.
Synonyms: 2-(Diethylamino)ethyl 4-amino-2-chlorobenzoate, 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl esterProducts: Ampres 10 mg/ml Injektionslösung, Ampres 20 mg/ml Injektionslösung