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Displaying results 241 - 250 of 10000 in total
  1. Drug

    Etanercept

    go.drugbank.com/drugs/DB00005
    ApprovedInvestigational

    [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids.

    Categories: Amino Acids, Peptides, and ProteinsProducts: BENEPALI 25MG ILO IN FER, ERELZI 25MG ILO IN FER
  2. Drug

    Darbepoetin alfa

    go.drugbank.com/drugs/DB00012
    ApprovedInvestigational

    Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.

    Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsProducts: ARANESP 50UG FS MIT ANS, ARANESP 100UG FS MIT ANS
  3. Drug

    Mozafancogene autotemcel

    go.drugbank.com/drugs/DB17723
    Investigational

    RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A

    Synonyms: Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying FANCA Gene RP-L102
  4. Drug

    Doxylamine

    go.drugbank.com/drugs/DB00366
    ApprovedInvestigationalVet approved

    It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.

    Mixtures: DICLECTIN DELAYED RELEASE TABLETS 10MG/10MG, BONJESTA® XR 20MGSynonyms: N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine, Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether
  5. Drug

    Somatrogon

    go.drugbank.com/drugs/DB14960
    ApprovedInvestigational

    Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood … It is a chimeric product generated by fusing three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal residues, from the beta chain of human chorionic gonadotropin (hCG) to the N-terminus and

    Synonyms: .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES OF HUMAN CHORIOGONADOTROPIN SUBUNIT .BETA. (CG-.BETA.)-(118-145)- PEPTIDE (220-247Categories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and Insulins
  6. Drug

    Hepatitis B immune globulin

    go.drugbank.com/drugs/DB05276
    ApprovedInvestigational

    During the process, viruses are deactivated, and in the final steps, solvents used in the preparation are removed. The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. … According to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first anti-cancer vaccine.

    Categories: Amino Acids, Peptides, and Proteins, Immune Sera and ImmunoglobulinsProducts: IMMUNOHBS 1000 UI/3ML, IMMUNOHBS 180 UI SOLUCIÓN INYECTABLE
  7. Drug

    Fimaporfin

    go.drugbank.com/drugs/DB17253
    Investigational

    Synonyms: 4,4'-(15,20-diphenyl-7,8(or 12,13 or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid, mixture of three isomers a, b and c (25%, 50%, 25%)
  8. Drug

    Trimipramine

    go.drugbank.com/drugs/DB00726
    ApprovedInvestigational

    Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.

    Synonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamineCategories: Tricyclics and Other Norepinephrine-reuptake Inhibitors
  9. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996. … [L10550] Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen.

    Mixtures: Phentermine and topiramate, Phentermine and topiramateCategories: Alimentary Tract and Metabolism, phentermine and topiramate
  10. Drug

    Coagulation Factor IX (Recombinant)

    go.drugbank.com/drugs/DB00100
    Approved

    It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric patients with congenital factor IX deficiency (Hemophilia B).

    Synonyms: Recombinant factor IX, Factor IX (Recombinant)Products: BeneFIX powder and solvent for solution for injection 500 IU/VIAL., BeneFIX , powder and solvent for solution for injection, 250 IU/Vial.