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Displaying results 241 - 250 of 10000 in total
  1. Drug

    Valsartan

    go.drugbank.com/drugs/DB00177
    ApprovedInvestigational

    ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis … with type 2 diabetes and in nondiabetic patients diagnosed with chronic kidney disease.

    Mixtures: AMVALH® 5 MG. /160 MG. /12. 5 MG.TABLETA RECUBIERTA., DAFIRO 5 MG/160 MGCategories: Angiotensin II Type 1 Receptor Blockers, Angiotensin 2 Receptor Blocker
  2. Drug

    Chlorothymol

    go.drugbank.com/drugs/DB19375
    Approved

    Chlorotymol is a [Thymol] derivative.

    Synonyms: 4-chloro-5-methyl-2-(1-methylethyl)phenol, Phenol, 4-chloro-5-methyl-2-(1-methylethyl)-
  3. Drug

    Iohexol

    go.drugbank.com/drugs/DB01362
    ApprovedInvestigational

    Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality. … Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.

    Mixtures: Dexlido M-C, Dyural 80 LM-CCategories: X-Ray Contrast Activity, X-Ray Contrast Media, Iodinated
  4. Drug

    Prasterone

    go.drugbank.com/drugs/DB01708
    ApprovedInvestigationalNutraceutical

    Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. … In November 2016, DHEA was approved (as Intrarosa) to treat women experiencing moderate to severe pain during sexual intercourse (dyspareunia), a symptom of vulvar and vaginal atrophy (VVA), due to menopause

    Categories: 17-Ketosteroids, Androgens and EstrogensSynonyms: 3-beta-hydroxy-5-androsten-17-one, 3β-hydroxyandrost-5-en-17-one
  5. Drug

    Zolmitriptan

    go.drugbank.com/drugs/DB00315
    ApprovedInvestigational

    Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine. … It is currently available in both tablet and nasal spray forms.[L12978]

    Categories: Serotonin-1b and Serotonin-1d Receptor Agonist, Serotonin 5-HT1 Receptor AgonistsSynonyms: 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one, (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
  6. Drug

    10-(4-Dimethylamino-5-Hydroxy-6-Methyl-Tetrahydro-Pyran-2-Yloxy)-8-Ethyl-1,8,11-Trihydroxy-7,8,9,10-Tetrahydro-Naphthacene-5,12-Dione

    go.drugbank.com/drugs/DB04131
    Experimental

    Synonyms: 10-(4-Dimethylamino-5-Hydroxy-6-Methyl-Tetrahydro-Pyran-2-Yloxy)-8-Ethyl-1,8,11-Trihydroxy-7,8,9,10-Tetrahydro-Naphthacene-5,12-Dione
  7. Drug

    Tavaborole

    go.drugbank.com/drugs/DB09041
    Approved

    Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes … Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).

    Synonyms: 5-Fluoro-2,1-benzoxaborol-1(3H)-ol, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
  8. Drug

    Clobazam

    go.drugbank.com/drugs/DB00349
    ApprovedIllicitInvestigational

    [A256963,A256868] This is likely because of clobazam's higher affinity to the α<sub>2</sub> subunit of the GABA<sub>A</sub> receptor, which mediates anxiolytic effects, than the α<sub>1</sub> subunit, … [A256913] Unlike older 1,4-benzodiazepines, clobazam has a better side-effects profile, particularly less sedative and amnesic effects.

    Categories: Benzodiazepines and benzodiazepine derivatives, GABA-A Receptor AgonistsSynonyms: 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione, 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine
  9. Drug

    Ferric oxide

    go.drugbank.com/drugs/DB11576
    ApprovedInvestigational

    It is one of the three main oxides of iron, the other two being iron(II) oxide (FeO) the rarer form, and iron(II,III) oxide (Fe3O4) which naturally as magnetite.

    Mixtures: Aveeno Calamine and Pramoxine Hydrochloride Anti Itch, L-Topical CALAMINE 8% ZINC OXIDE 8%Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Cholesterol

    go.drugbank.com/drugs/DB04540
    ApprovedInvestigationalWithdrawn

    The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.

    Categories: P-glycoprotein inhibitorsSynonyms: (3β,14β,17α)-cholest-5-en-3-ol, Cholest-5-en-3beta-ol