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Ephedrine
go.drugbank.com/drugs/DB01364ApprovedInvestigationalIt is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine … Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine].
Mixtures: COPHADYL-E COUGH LINCTUS, BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 MLProducts: Formula C34 Tab .13mg, Ephedrinhydrochlorid Aguettant 3 mg/ml Injektionslösung in FertigspritzeFulvestrant
go.drugbank.com/drugs/DB00947ApprovedInvestigationalWhile it is used as monotherapy for the treatment of breast cancers, it is also used in combination with [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative … It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.
Products: FULVESTRANT 250 MG/5ML SOLUCION INYECTABLE EN JERIGA PRECARGADA, FULTRANT ® 250MG/ 5ML SOLUCIÓN PARA INYECCIÓN EN JERINGA PRELLENADACabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigationalIt was first approved by the FDA on June 17, 2010.[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376]
Synonyms: -DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA.-TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE)Products: CABAZITAXEL EG, CABAZRED 60 MG/1.5 MLCyanocobalamin
go.drugbank.com/drugs/DB00115ApprovedInvestigationalNutraceuticalThis drug was initially approved by the FDA in 1942 [FDA label]. … Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt.
Mixtures: Multivit Et Fer Ampoules Et Comprimes, APIKOBAL 250MG/250MG/1MG FİLM KAPLI TABLET, 30 ADETProducts: CIANOCOBALAMINA EG, BETOLVEX 1MG/ML AMPULRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalHowever there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … FDA approved on July 1, 2011.
Products: RIVAROXABAN EG, RIVAROXABAN EG STADAIcatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigational[A4017,A263041] It was investigated as a potential treatment of hereditary angioedema (HAE) as bradykinin was implicated in HAE swelling; specifically, mice lacking B<sub>2</sub> receptors showed reduced … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema.
Categories: Drugs Used in Hereditary AngioedemaProducts: ICATIBANT EG, İCATİN 30MG/3ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖRPravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigational[T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. … [L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained.
Products: PRAVASTATINA EG, PRAVASTATIN HEU 10MG NETEzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigational[A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings … The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the
Mixtures: ATOZET (10MG/10MG), ATOZET TABLET 10MG/10MGProducts: EZETIMIBE EG, Mac-Zet (Ezetimibe Tablets USP 10 mg)Cinacalcet
go.drugbank.com/drugs/DB01012ApprovedInvestigationalIt is used to treat hyperparathyroidism due to parathyroid tumours or renal failure. … Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.
Synonyms: (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine, N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amineProducts: CINACALCET EG, TICAGRELOR EGTamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigational[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments. … [A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799]
Synonyms: 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene, (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamineProducts: TAMOXIFENE EG, Tamone Tab 10mg