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Displaying results 2491 - 2500 of 10000 in total
  1. Drug

    9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid

    go.drugbank.com/drugs/DB04227
    Experimental

    Synonyms: (6R)-5-Acetamido-6-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-2,6-anhydro-3,5-dideoxy-L-threo-hex-2-enonic acid, 9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid
  2. Drug

    INCB-086550

    go.drugbank.com/drugs/DB18901
    Investigational

    INCB-086550 is under investigation in clinical trial NCT04629339 (Study of INCB086550 in Select Solid Tumors).

    Synonyms: 3-PYRROLIDINECARBOXYLIC ACID, 1-((7-CYANO-2-(3'-((3-(((3R)-3-HYDROXY-1-PYRROLIDINYL)METHYL)-1,7-NAPHTHYRIDIN-8-YL)AMINO)-2,2'-DIMETHYL(1,1'-BIPHENYL)-3-YL)-5-BENZOXAZOLYL)METHYL)-, (3R)-
  3. Drug

    Coenzyme F420

    go.drugbank.com/drugs/DB03913
    Experimental

    Synonyms: N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-γ-L-glutamyl}-L-glutamate, coenzyme γ-F420-2Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring
  4. Drug

    Norclobazam

    go.drugbank.com/drugs/DB17092
    Investigational

    Synonyms: 1h-1,5-benzodiazepine-2,4(3h,5h)-dione, 8-chloro-1-phenyl-7-chloro-5-phenyl-1,2,4,5-tetrahydro-3h-1,5-benzodiazepine-2,4-dione, Clobazam metabolite m9Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  5. Drug

    Idasanutlin

    go.drugbank.com/drugs/DB12325
    Investigational

    Idasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.

    Synonyms: BENZOIC ACID, 4-((((2R,3S,4R,5S)-3-(3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2-DIMETHYLPROPYL)-2-PYRROLIDINYL)CARBONYL)AMINO)-3-METHOXY-Categories: Heterocyclic Compounds, 1-Ring, Proto-Oncogene Proteins c-mdm2, antagonists & inhibitors
  6. Drug

    Doxecitine

    go.drugbank.com/drugs/DB02594
    ApprovedInvestigational

    It is an essential component of the deoxyribonucleotide pool required for DNA synthesis and repair. … Doxecitine is a synthetic form of the naturally occurring pyrimidine deoxyribonucleoside deoxycytidine.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: MT-1621 COMPONENT 2'-DEOXYCYTIDINE, 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2- yl)pyrimidin-2(1H)-one
  7. Drug

    Erdosteine

    go.drugbank.com/drugs/DB05057
    ApprovedInvestigational

    It is a _thiol_ derivative produced for the clinical management of chronic obstructive bronchitis, in addition to infective exacerbations of chronic bronchitis. … Erdosteine is a drug that causes a breakdown of mucus, also known as a _mucolytic_ agent.

    Categories: Heterocyclic Compounds, 1-RingProducts: ENZEVİN 175 MG/5 ML SUSPANSIYON ICIN KURU TOZ, 100 ML, EVOSTEN 175 MG/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 100 ML
  8. Drug

    Atorvastatin

    go.drugbank.com/drugs/DB01076
    ApprovedInvestigational

    [A181087, A181406] Some evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within five years) statin use leads to a 20%-22% relative reduction in … More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid.

    Mixtures: Triveram 10 mg/5 mg/5 mg Filmtabletten, TRIVERAM FILM-COATED TABLET 10 mg/5 mg/5 mgCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitors
  9. Drug

    Posaconazole

    go.drugbank.com/drugs/DB01263
    ApprovedInvestigationalVet approved

    Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.

    Categories: Heterocyclic Compounds, 1-Ring, 14-alpha Demethylase InhibitorsProducts: POSACONAZOLO EG, POSACONAZOLO EG STADA
  10. Drug

    Esmolol

    go.drugbank.com/drugs/DB00187
    ApprovedInvestigationalWithdrawn

    Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. … It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses.

    Categories: Adrenergic beta-1 Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate, 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester