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Displaying results 2501 - 2510 of 10000 in total
  1. Drug

    Anlotinib

    go.drugbank.com/drugs/DB11885
    Investigational

    Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.

    Synonyms: 1-((4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropan-amineCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Elimusertib

    go.drugbank.com/drugs/DB19041
    Investigational

    Elimusertib is under investigation in clinical trial NCT05071209 (Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors).

    Synonyms: 1,7-naphthyridine, 2-((3r)-3-methyl-4-morpholinyl)-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)-Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Fosmanogepix

    go.drugbank.com/drugs/DB15183
    Investigational

    Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).

    Synonyms: [2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen phosphate
  4. Drug

    Tomivosertib

    go.drugbank.com/drugs/DB15219
    Investigational

    Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'-dione
  5. Drug

    Fimepinostat

    go.drugbank.com/drugs/DB11891
    Investigational

    Fimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.

    Synonyms: 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]methylamino]-, N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino)pyrimidine-5-carboxamideCategories: Heterocyclic Compounds, 1-Ring, Phosphatidylinositol 3-Kinases, antagonists & inhibitors
  6. Drug

    Osugacestat

    go.drugbank.com/drugs/DB12006
    Investigational

    Osugacestat (BMS-906024) has been used in trials studying the treatment of Cancer, Lymphoblastic Leukemia, Acute T-cell, and Precursor T-Cell Lymphoblastic Lymphoma.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (2R,3S)-N1-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl)succinamide, Butanediamide, N1-((3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-2,3-bis(3,3,3-trifluorophenyl)-, (2R,3S)-
  7. Drug

    ADH-1

    go.drugbank.com/drugs/DB05485
    Investigational

    At the end of 2006, the Company also completed patient enrollment in our single-agent Phase Ib/II and Phase II trials of ADH-1. … ADH-1 may have utility in a wide variety of cancers as N-cadherin is overexpressed in a variety of tumors.

    Synonyms: l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfide
  8. Drug

    Rifaximin

    go.drugbank.com/drugs/DB01220
    ApprovedInvestigational

    It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of overt hepatic encephalopathy recurrence; as well as diarrhea-predominant irritable bowel … syndrome (IBS-D) in adult women and men.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: Rifamycin L 105, Rifamycin L 105SV
  9. Drug

    Tirofiban

    go.drugbank.com/drugs/DB00775
    ApprovedInvestigational

    It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation. … Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery.

    Synonyms: (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid, N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosineProducts: AGRASEL 12.5 MG/50 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN FLAKON, 1 ADET, TIROSTU 12.5 MG/50 ML IV KONSANTRE İNFÜZYONLUK ÇÖZELTİ, 1 ADET
  10. Drug

    [2-(1-Amino-2-Hydroxy-Propyl)-4-(4-Fluoro-1h-Indol-3-Ylmethyl)-5-Hydroxy-Imidazol-1-Yl]-Acetic Acid

    go.drugbank.com/drugs/DB01674
    Experimental

    Synonyms: [2-(1-Amino-2-Hydroxy-Propyl)-4-(4-Fluoro-1h-Indol-3-Ylmethyl)-5-Hydroxy-Imidazol-1-Yl]-Acetic Acid