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Displaying results 2501 - 2510 of 10000 in total
  1. Drug

    Levocarnitine

    go.drugbank.com/drugs/DB00583
    ApprovedInvestigational

    It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

    Synonyms: 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt, (R)-CarnitineMixtures: Q 10 Suprabio +L-Carnitine, Q-GEL CARNI SOFTSULE
  2. Target

    Frizzled-5

    go.drugbank.com/bio_entities/BE0014104
    TargetHumans

    Receptor for Wnt proteins (PubMed:10097073, PubMed:20530549, PubMed:26908622, PubMed:9054360). Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling (By sim...

    Polypeptides: Frizzled-5Synonyms: Fz-5
  3. Drug

    Abciximab

    go.drugbank.com/drugs/DB00054
    ApprovedWithdrawn

    Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. … It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and smooth muscle cells.

    Products: CLOTİNAB 10 MG/5 ML IV ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN FLAKON, 1 ADET, ReoPro 2 mg/ml Injektionslösung oder Infusionslösung
  4. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. … It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels.

    International brands: Gen-MetforminMixtures: JARDIANCE DUO® 5 MG/1000 MG, JARDIANCE DUO® 5 MG / 850 MG
  5. Drug

    Procaine

    go.drugbank.com/drugs/DB00721
    ApprovedInvestigationalVet approved

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215]. … A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.

    Synonyms: 2-Diethylaminoethyl p-aminobenzoate, β-(diethylamino)ethyl 4-aminobenzoateProducts: NTCAIN 50 MG/5 ML IM AMPUL , 50 ADET, NTCAIN 50 MG/5 ML IM AMPUL , 10 ADET
  6. Drug

    Lamotrigine

    go.drugbank.com/drugs/DB00555
    ApprovedInvestigational

    Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. … Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It is approved for use in more than 30 countries.

    Synonyms: 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazineInternational brands: Lameptil S
  7. Drug

    Cisapride

    go.drugbank.com/drugs/DB00604
    ApprovedWithdrawn

    The FDA issued a warning letter regarding this risk to health care professionals and patients. … In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: DISPEPRID 5 MG TABLET, 30 ADET, GUARPOSID - 5
  8. Drug

    Dexmedetomidine

    go.drugbank.com/drugs/DB00633
    ApprovedInvestigationalVet approved

    An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

    Synonyms: (+)-4-((S)-α,2,3-trimethylbenzyl)imidazole, (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazoleCategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor Agonists
  9. Drug

    Tropisetron

    go.drugbank.com/drugs/DB11699
    ApprovedInvestigationalWithdrawn

    As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting … Tropisetron is an indole derivative with antiemetic activity.

    Categories: Serotonin 5-HT3 Receptor Antagonists, Cytochrome P-450 SubstratesProducts: NAVOBAN 5 MG 1 AMPUL, Navoban 5 mg - Kapseln
  10. Drug

    Vortioxetine

    go.drugbank.com/drugs/DB09068
    ApprovedInvestigational

    receptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. … Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional

    Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT1 Receptor AntagonistsProducts: KELAC 5 MG, BRINTELLIX 5 MG FILM KAPLI TABLET ,56 TABLET