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Displaying results 2511 - 2520 of 10000 in total
  1. Drug

    Esculin

    go.drugbank.com/drugs/DB13155
    Approved

    Esculin is found in barley. … ) and in daphnin (the dark green resin of Daphne mezereum).

  2. Drug

    Iscotrizinol

    go.drugbank.com/drugs/DB15468
    Investigational

    Mixtures: Sun Project Skin-relief Suncream
  3. Drug

    Odevixibat

    go.drugbank.com/drugs/DB16261
    ApprovedInvestigational

    Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC … [A236808] Odevixibat was granted FDA and Health Canada approval on 20 July 2021 and 13 November 2023 respectively.[L34793,L49535]

  4. Target

    Sigma non-opioid intracellular receptor 1

    go.drugbank.com/bio_entities/BE0000156
    TargetHumans

    Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of d...

    Synonyms: SIG-1R
  5. Drug

    Pyridoxal phosphate

    go.drugbank.com/drugs/DB00114
    ApprovedInvestigationalNutraceutical

    This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is tra...

    Mixtures: EnlCategories: Vitamin B Complex
  6. Drug

    Sofosbuvir

    go.drugbank.com/drugs/DB08934
    ApprovedInvestigational

    in combination with other antivirals for all six genotypes of Hepatitis C [L852]. … Its use has also proven successful in the treatment of HCV in patients co-infected with HIV [A19627].

  7. Drug

    Levocarnitine

    go.drugbank.com/drugs/DB00583
    ApprovedInvestigational

    It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

    Synonyms: 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt
  8. Drug

    Agrostis gigantea pollen

    go.drugbank.com/drugs/DB10403
    Approved

    Agrostis gigantea pollen is mainly used in allergenic testing.

    Mixtures: Mixture of Six Standardized Grasses
  9. Target

    C-C motif chemokine 5

    go.drugbank.com/bio_entities/BE0000975
    TargetHumans

    Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). … The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) (PubMed:1380064, PubMed:15923218, PubMed:16791620, PubMed:8525373

    Synonyms: SIS-delta
  10. Drug

    Astemizole

    go.drugbank.com/drugs/DB00637
    ApprovedWithdrawn

    Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. … It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.